Professor Jason W Chin
Jason Chin is a Group Leader at the Medical Research Council Laboratory of Molecular Biology (MRC-LMB), and a fellow in the Natural Sciences at Trinity College, Cambridge. Jason was an undergraduate at Oxford, obtained his PhD as a Fulbright grantee from Yale, and was a Damon Ruyon Fellow at Scripps. From July 2003 to early 2007 he was a tenure-track group leader at MRC-LMB. He became an EMBO Young Investigator in 2005 and a tenured group leader in 2007. He was awarded the Francis Crick Prize Lectureship by the Royal Society in 2009. His laboratory's work spans chemical biology and synthetic biology. He created the first method to systematically expand the eukaryotic genetic code. He created and applied the first method to introduce photochemical probes into proteins in both prokaryotic and eukaryotic cells and map protein interactions in vivo. His lab has evolved and reprogrammed the ribosome, long thought un-evolvable, invented new forms of gene regulation, provided insight into ribosome function, created tools for genetically installing post-translational modifications, and created new genetic codes in cells. His lab continues to apply the tools they have developed to provide insight into biological processes, with a particular emphasis on deciphering the role of post-translational modifications in regulating organismal function.
Abstract
Reprogramming the code of life
