Polymers in therapeutics: polymer nanomedicines
Convener:
Giuseppe Battaglia, University of Sheffield, UK
Co-Convener: Ian Hamley, University of Reading, UK
Co-Convener: María Jesús Vicent, CIPF, Spain
Programme:
Wednesday 14 July (morning and afternoon)
Thursday 15 July (morning and afternoon)
Symposium Information
Abstracts on the following topics are welcomed:
- Drug and gene delivery
- Tissue engineering and regenerative medicine
- Diagnostics and medical imaging
- Biomaterials and medical devices
Keynote Speaker
Smart micelles and vesicles from PEG-polypeptide block copolymers as nanocarriers for gene and drug delivery
Kazunori Kataoka, University of Tokyo, Japan
Invited Speakers
Nanomedicines with Polymers - from Drug Delivery Morphologies to Stem Cell Differentiation
Dennis Discher, University of Pennsylvania, USA
Self-assembled beta-hairpin peptides-responsive gels and templates for hybrid materials
Darrin Pochan, University of Delaware, USA
Polymersome-based artificial organelles
Jan van Hest, Radboud University Nijmegen, The Netherlands
Speakers
RAFT-Synthesized Polymer Therapeutics for Gene Silencing
Volga Bulmus, University of New South Wales, Australia
From Test Tube to In Vivo Protection : Polyelectrolyte Microcapsules as Versatile Antigen Carriers
Bruno de Geest, Ghent University, Belgium
Poly (gamma-Glutamic Acid): a Biodegradable, Biocompatible and Naturally Produced Polymer as a Promising Candidate for Regenerative Medicine Applications
Cristina Gentilini, Imperial College London, UK
Physicochemical Characterisation of Novel DES-Polyacetal Block Copolymers for the Treatment of Hormone-Dependent Cancer
Vanessa Giménez-Navarro, Centro de Investigación Príncipe Felipe Valencia, Spain
Use of SANS and EPR to study the interaction of an endosomolytic polyamidoamine ISA23 with vesicles mimicking intracellular membranes
Peter Griffiths, Cardiff University, UK
Exploiting Supercritical Carbon Dioxide To Create Novel Polymeric Drug Delivery Devices
Steve Howdle, University of Nottingham, UK
Phosphine-mediated one-pot thiol-ene "click" approach to polymer-protein conjugates
Mathew Jones, University of Warwick, UK
"One pot" loading of hydrophilic model drugs in polymersomes using co-flow microfluidic chip
Jean-François Le Meins, University of Bordeaux, France
Photo-responsive polymer vesicles: bursting and wrinkling
Min-Hui Li, Institut Curie/CNRS, France
Efficient Intracellular delivery of bioactive molecules using pH sensitive polymersomes
Marzia Massignani, University of Sheffield, UK
Development of Implantable Polymer Rods for Minimum Invasive Cancer Chemotherapy
Norased Nasongkla, Mahidol University, Thailand
Advanced Poly(alkyl cyanoacrylate) Nanoparticles As Promising Therapeutic Agents for Alzheimer's Disease And Intracellular Trafficking
Julien Nicolas, Université Paris-Sud, France
Polymeric Nanoreactors for Enzyme Therapy in Oxidative Stress
Cornelia G. Palivan, University of Basel, Switzerland
Polymersome penetration into human skin
Carla Pegoraro, University of Sheffield, United Kingdom
Template-Polymerised, Bio-Reducible, Branched Polyamine Vectors for siRNA Delivery
James Serginson, Imperial College London, UK
Development of highly branched modified poly(N-isopropyl acrylamide) polymers responsive to bacteria and their use in the reduction of bacterial burden of infected wounds
Joanna Shepherd, University of Sheffield, UK
Complex polymer architectures with pending ligands prepared via click chemistry or isocyanate chemistry for the delivery of platinum anti-cancer drugs
Martina Stenzel, University of New South Wales, Australia
Teaching Polymers How to Act Like Proteins: Antimicrobial and Cell Penetrating Activity
Greg Tew, University of Massachusetts, Amherst, USA
Hyperbranched Polymers in Theranostics
Kristofer Thurecht, University of Queensland, Australia
Amphiphiles containing rigid hydrogen-bonding moieties: Syntheses, characterization, evaluation of self-assembly behaviors and drug delivery applications
Shrinivas Venkataraman, Institute of Bioengineering and Nanotechnology, Singapore
Poster Presenters
Preparation and In Vitro Evaluation of Gelatin Graft Copolymers/Hydroxyapatite Bionanocomposites
Ahmed Haroun, National Research Centre, Egypt
Development of polyelectrolyte complex microparticles of natural polymers for drug delivery
Nirmala Devi, Tezpur University, India
"Smart" Functional Hybrid Polymer/Gold Nanoparticles
Cyrille Boyer, CAMD, UNSW, Australia
Unbreakable Codes in Electrospun Fibers to Stop Medicine Counterfeiting
Chaobo Huang, Gent University, Belgium
The multiple morphologies of pH-responsive di- and triblock copolymers: from asymmetric vesicles to octopi and hexagonal vesicles to highly branched wormlike micelles
Adam Blanazs, University of Sheffield, United Kingdom
Polymer-Peptide Hydrogels: Towards Smart Drug Delivery Scaffolds
Paul Topham, Aston University, United Kingdom
Thermoresponsive Biocompatible Block Copolymers with Antimicrobial Activity
Jeppe Madsen, University of Sheffield, United Kingdom
Imaging amphiphilic block copolymer interactions with lipid bilayers
Millicent Firestone, Argonne National Laboratory, United States
Thermo-responsive and biocompatible Poly(N-vinylcaprolactam) coated magnetic nanoparticles for biomedical applications: Synthesis and characterization
Simone Medeiros, University of São Paulo, Brazil
Hydrophilic Cationic Core Cross-linked Star Polymers siRNA Nanocarriers: Synthesis, Characterization and Evaluation
Kyriaki Pafiti, University of Cyprus, Cyprus
Selective Fluorescent Labelling of an Amphiphilic Biocompatible Block Copolymer
Nicholas Warren, University of Sheffield, United Kingdom
Time-Resolved Small-Angle Neutron Scattering as a Tool for Studying Controlled Release from Liposomes using Polymer-Enzyme Conjugates
Peter Griffiths, Cardiff University, United Kingdom
The interaction of model polymer therapeutics with mucous
Peter Griffiths, Cardiff University, United Kingdom
Chitosan-based Nanogel Delivery Systems: Characterization and Toxicological Evaluation
Catherine A. Schütz, EPFL-SV-IBI-LMRP, Switzerland
Resorbable Calibrated Microspheres for Therapeutic Embolization
Laurence Moine, CNRS, Châtenay-Malabry, France
Investigation of functional structure relationship between different PDMAEMA-based architectures and cellular uptake
Anja Schallon, University of Bayreuth, Germany
Novel electrospun micro- and nanofibrous materials possessing antimicrobial properties for wound dressing applications
Milena Ignatova, Bulgarian Academy of Sciences, Bulgaria
Bio-responsive Small Molecule Polyamines as Non-Cytotoxic Alternative to Polyethylenimine
Joachim Steinke, Imperial College London, United Kingdom
Solution Conformation of Polymer-Drug Conjugates: contrast-variation small-angle neutron scattering (SANS) as a tool to elucidate the microstructure of uni-molecular aggregates
Alison Paul, Cardiff University, United Kingdom
Crosslinked polymeric micelles: the new golden standard for tumour targeted drug delivery?
Cornelus van Nostrum, Utrecht University, Netherlands
Investigation of Croscarmellose sodium as an excipient for Fast releasing tablets of Olanzapine
Venkateskumar Krishnamoorthy, KMCH College of Pharmacyy, India
Injectable Biodegradable Polymers For The Delivery Of Camptothecin Anti-Cancer Drugs
Olcay Mert, Middle East Technical University, Turkey
Glycerolipidic Prodrug of Didanosine Encapsulated Into PEGylated Nanoparticles: An Approach To Treat HIV-1 Associated Dementia
Julien Nicolas, Univ. Paris-Sud 11, France
Thermosensitive Amphiphilic Polymer as in-Situ Gelation Biomaterials for Injectable Vitreous Substitute
Masahiko Annaka, Kyushu University, Japan
Tailor-made Polycations for Gene-Delivery Applications
Christopher V. Synatschke, University of Bayreuth, Germany
pH-Sensitive and Cross-linkable Polymersomes for Applications in Synthetic Biology as part of biomedical Applications
Jens Gaitzsch, Leibniz Intitute of Polymer Reasearch, Germany
An on-line combine analysis system for polymersome purification and characterisation
Linge Wang, University of Sheffield, United Kingdom
Polymersome mediated siRNA delivery
Nisa Patikarnmonthon, University of Sheffield, United Kingdom
pH-responsive diblock copolymers based on HEGMA and DEAEMA functionalities: Investigation of their ability to act as drug delivery systems and in-vitro cytotoxicity studies
Petri Papaphilippou, University of Cyprus, Cyprus
Versatile Surface Functionalization of Polymer Vesicles
Stefan Egli, Universität Basel, Switzerland
Oligopeptide-grafted polycyclooctene for gene therapy
Delphine Chan-Seng, University of Massachusetts, United States
Dextran coated gold nanorods for targeted photothermal ablation of inflammatory macrophages
Choi Rayun, Yosei University, Republic of Korea
A self-organized pH-responsive glycol chitosan nonagel for tumor targeting
Oh Nam Muk, The Catholic University of Korea, Republic of Korea
A pH-sensitive multifunctional bio-polymeric nanocarrier for protein delivery
Lee Bo Reum, The Catholic University of Korea, Republic of Korea
Synthesis of hydrophilic bioconjugate polymers by nitroxide mediated polymerization
Nadège Handké, Université de Provence, Marseille, France
Polyelectrolyte complexes for improved drug delivery of therapeutic proteins
Marina Inés Giannotti, Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain
Injectability of Polymer Microparticles Prepared Using Supercritical Carbon Dioxide
Andrew Naylor, Critical Pharmaceuticals Ltd, United Kingdom
Randomly Methylated-Beta-Cyclodextrin (RAMEB) Alters the Photostability of Midazolam in Aqueous Solution
Beverley Glass, James Cook University, Australia
Effective encapsulation and protease protection of proteins using polymersome
Denis Cecchin, University of Sheffield, United Kingdom
A three-component cancer treatment using an alkylated DNA based drug delivered with PMPC-PDPA based polymersomes followed by alkylation chemotherapy
Christopher Millington, University of Sheffield, United Kingdom
Specific optical imaging of glioblastoma with integrin-targeting gold nanorods
Choi Jihye, Yonsei University, Republic of Korea
Polymer Stabilised Emulsions for the Treatment of HIV/AIDS
Rebecca Slater, University of Liverpool, United Kingdom
Tuning the crystallinity of poly(3-hydroxybutyrate) in order to match its application as drug carrier
Lilian Lacerda de Almeida, Universidade de Sao Paulo, Brazil
The synthesis of novel microgel particles based on 2-hydroxyethylmethacrylate and 2-hydroxyethylacrylate
Joseph Cook, University of Reading, United Kingdom
Carbopol®-based in situ gelling systems for the improved delivery of ocular therapeutics
Richard Cave, University of Reading, United Kingdom
Development of a Vascular Graft Using Electrospun Polyurethane
Andrew Whitton, University of Strathclyde, United Kingdom
Symposium Sponsor
We are grateful to Warwick Effect Polymers for their sponsorship support of the Polymers in Therapeutics symposium.

