Programme
Day 1- Understanding and measuring molecular interactions
- The fundamentals of molecular interactions
- How molecular interactions control the formation of macromolecules and coordinate biological processes
- Techniques for measuring molecular interactions
- Practical session: the de novo design of a ligand for a protein
Day 2- Synthesis for chemical biology
- Peptide and oligonucleotide synthesis
- Recombinant protein expression
- Exploiting enzymes in synthetic organic chemistry
- Practical session: synthesis of a small molecule using a biological approach
Day 3- Advanced topics in chemical biology
Three emerging topics will be covered on Day-3:
- Understanding and manipulating protein-protein interactions
- Enzymes in organic synthesis: Directed evolution and advanced applications
- Advanced methods for protein synthesis and modification
