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Highlights in Chemical Science

News from across RSC Publishing.

Issue 10

Global climate change

Much speculation and confusion exists over climate change, and this has led a team of eminent scientists headed by Robert Watson, former White House environmental advisor and now advisor to the World Bank, to call for a balanced discussion. The group feel that information is being misused to support ideological viewpoints. They examine the scientific evidence to date and emphasise the need for closer and broader monitoring of the environment. 

Bimetallic complexes

A series of bimetallic complexes where rhodium and ruthenium are bridged by sulfur, selenium or tellurium have been made by a team of Japanese scientists, led by Yasushi Mizobe. These are currently of interest because complexes with two different metal atoms promise different properties and improved catalytic performance. Indeed, Mizobe says they 'might provide a clue to innovate new complexes that model the enzyme hydrogenase', which produces hydrogen gas from water. 

Mother Nature's way

Jack Baldwin and co-workers from the Universities of Oxford and London have discovered a novel biomimetic method for the synthesis of natural products. Mimicking nature, the generation of complex structures has been achieved via a biosynthetic pathway. Natural products ( )-lucidene and (  )-alboatrin were formed using a method for o-quinone methide generation. An important development in accessing the wealth of structures available in nature, this new methodology will play a vital role in the future of drug discovery.  

More efficient algorithms

Molecular dynamics simulations that use 'first principles' potential energy functions (based on performing quantum chemistry calculations on-the-fly) are pushing molecular simulation into exciting new areas, but these calculations remain very computationally expensive. John Herbert and Martin Head-Gordon from the University of California, Berkeley, US, have developed a method to accelerate such calculations without the usual problem of introducing severe approximations. Herbert hopes that this work will inspire progress toward more efficient algorithms. 

Essential Elements

News from across the globe

RSC events in the US and South Korea

What happened next?

'Forward linking' announced

Calling all chemical biologists!

Chemical Biology, a sister-title to Chemical Science and Chemical Technology is being launched soon

Research Highlights

A leap forward for chemical genetics

Frogs can now be used as model organisms for chemical genetic screens.

Solving the greenhouse gas riddle

A team of UK researchers has helped uncover the mystery of exactly how soil bacteria catalyse the reduction of nitrous oxide.

Copper complexes recognise DNA bases

Researchers are using copper complexes to look into the fine detail of the structure and folding pattern of nucleic acids.

Theoretical future for drug design

Swiss researchers have found a way to search for new and improved versions of common drugs.

Peptide mimics to the rescue

A new kind of wound-healing drug could be on the way thanks to a team of UK researchers.

Delicate deprotection

Researchers claim to have developed a new protecting group.

Liquid crystals give chiral surprise

A team of Japanese and Korean researchers has mixed together banana- and rod-shaped molecules to give surprising results.

Too many sperm spoil the egg

US scientists claim to have developed a lab on a chip that mimics egg cell fertilisation in live pigs.

Carbonates hold promise for bioreactors

Carbonates could hold the key to new, effective polyelectrolyte biosensors and bioreactors.

Bacteria lose their virulence

Researchers have evidence that synthetic compounds stop bacteria attaching themselves so effectively to host cells.

Getting wired up to nanotubes

Researchers have made conducting polymer nanorods and nanotube Y-shaped junctions.

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