Issue 6, 2007

Surface plasmon resonance as a time-resolved probe of structural changes in molecular films: considerations for correlating resonance shifts with adsorbate layer parameters

Abstract

Surface plasmon resonance (SPR) spectroscopy is an efficient probe of transient structural changes in molecular films. To analyze kinetic SPR data for such systems, generally it is necessary to adapt an adequate theoretical framework that would allow one to express the measured optical quantities (time-dependent shifts of the resonance angle or wavelength) in terms of the structural parameters (layer thickness, mass density, or surface coverage) of the sample molecules. We present here theoretical calculations and illustrative experimental results to address certain essential elements of this type of data analysis for transient SPR systems. The phenomenological framework we consider here is based on multilayer reflectivity calculations, and can be applied to a broad class of systems involving ordered molecular layers on supporting gold films. A typical application of these calculations is demonstrated through the analysis of specific SPR experiments designed to probe the kinetics of pH-induced structural changes in a molecular film of 11-mercaptoundecanoic acid (MUA) on a thin gold film.

Graphical abstract: Surface plasmon resonance as a time-resolved probe of structural changes in molecular films: considerations for correlating resonance shifts with adsorbate layer parameters

Article information

Article type
Paper
Submitted
27 Oct 2006
Accepted
20 Mar 2007
First published
02 Apr 2007

Analyst, 2007,132, 524-535

Surface plasmon resonance as a time-resolved probe of structural changes in molecular films: considerations for correlating resonance shifts with adsorbate layer parameters

C. M. Pettit and D. Roy, Analyst, 2007, 132, 524 DOI: 10.1039/B615615K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements