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Analyst, 2009, 134, 1745 - 1750, DOI: 10.1039/b909080k
Nanoshell-based substrates for surface enhanced spectroscopic detection of biomolecules
Carly S. Levin, Janardan Kundu, Aoune Barhoumi and Naomi J. Halas
Nanoshells are optically tunable core–shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.
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