Journal of the Chemical Society, Chemical Communications
Journal of the Chemical Society, Chemical Communications was published between 1972 - 1995.
Paper
J. Chem. Soc., Chem. Commun., 1990, 1526 - 1528, DOI: 10.1039/C39900001526
A novel hydrogel matrix on gold surfaces in surface plasmon resonance sensors for fast and efficient covalent immobilization of ligands
Stefan Löfås and Bo Johnsson
Gold surfaces intended for surface plasmon resonance sensors have been derivatized with a flexible matrix composed of carboxymethylated dextran to provide fast and efficient coupling of proteins and other ligands at low concentrations using the principles of ionic pre-concentration; these hydrophilic and protein compatible hydrogel surfaces allow increased immobilization capacity as compared to monolayer based coatings, for applications in biospecific interaction analysis.
