SCHEDULED MAINTENANCE
Amide cuprate reagents attack the less hindered carbon atom of epoxides to give 1,2-amino alcohols in good yields; this procedure is applied to the synthesis of an aziridine alcohol bearing a carborane framework which is a potentially useful 10B carrier for boron neutron capture therapy.
Y. Yamamoto, N. Asao, M. Meguro, N. Tsukada, H. Nemoto, N. Sadayori, J. G. Wilson and H. Nakamura, J. Chem. Soc., Chem. Commun., 1993, 1201 DOI: 10.1039/C39930001201
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