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Journal of the Chemical Society, Chemical Communications


Journal of the Chemical Society, Chemical Communications was published between 1972 - 1995.

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Paper

J. Chem. Soc., Chem. Commun., 1995, 2521 - 2522, DOI: 10.1039/C39950002521


Total synthesis of milbemycin G: assembly and completion of the synthesis

Simon Bailey, Aphiwat Teerawutgulrag and Eric J. Thomas


The Wittig reaction between phosphonium salt 1 and the hydroxybutenolide 2 followed by deprotection, macrocyclisation, and reduction gives the 6-hydroxymilbemycin E 9 which by further cyclisation is converted into milbemycin G 11.