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Chem. Commun., 2005, 4551 - 4553, DOI: 10.1039/b505737j


A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry

Neil K. Garg, Carolyn C. Woodroofe, Christopher J. Lacenere, Stephen R. Quake and Brian M. Stoltz


A mild heterogeneous, ligand-free protocol for Sonogashira and Heck couplings has been developed and used to access several biologically important deoxynucleoside derivatives in a facile manner.

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