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Communication

Chem. Commun., 2007, 2968 - 2970, DOI: 10.1039/b707524c

Reversible photopadlocking on double-stranded DNA

Kenzo Fujimoto, Shigeo Matsuda, Yoshinaga Yoshimura, Takehiro Ami and Isao Saito

We describe a highly efficient method for reversible photocircularization of oligonucleotide (ODN) on a double-stranded DNA template: 5-carboxyvinyl-2-deoxyuridine-containing ODN was reversibly circularized around the target sequence of the double-stranded plasmid DNA resulting in formation of a catenated plasmid.

Graphical abstract image for this article (ID: b707524c)