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Communication
Chem. Commun., 2007, 4872 - 4874, DOI: 10.1039/b712421j
Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles
Juewen Liu and Yi Lu
Using a Cu2+-dependent DNA ligation DNAzyme, a colorimetric sensor for Cu2+ has been developed based on directed assembly of DNA-functionalized gold nanoparticles by the ligation product, and such ligation DNAzyme-based sensors are intrinsically more sensitive than cleavage DNAzyme systems due to the lack of background.
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