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Communication

Chem. Commun., 2008, 3245 - 3247, DOI: 10.1039/b804812f

Reversible siRNA–polymer conjugates by RAFT polymerization

Karina L. Heredia, Thi H. Nguyen, Chien-Wen Chang, Volga Bulmus, Thomas P. Davis and Heather D. Maynard

A straightforward synthetic method to prepare pyridyl disulfide end functionalized poly(PEG acrylate) by RAFT polymerization for efficient and reversible conjugation to siRNA is described.

Graphical abstract image for this article (ID: b804812f)