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Communication

Chem. Commun., 2009, 1046 - 1048, DOI: 10.1039/b817590j

Formation and dissolution of hen egg white lysozyme amyloid fibrils in protic ionic liquids

Nolene Byrne and C. Austen Angell

The formation of amyloid fibrils from non-disease-related proteins demonstrates that any protein can adopt this rogue form; we show that it is possible to use protic ionic liquids to fibrilize hen egg white lysozyme, and then subsequently to dissolve the fibrils with up to 72% restoration of enzymatic activity.

Graphical abstract image for this article (ID: b817590j)