Issue 47, 2009
From the journal:

Chemical Communications

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing†

Ga-Lai Law,a   Robert Pal,a   Lars O. Palsson,a   David Parker*a  and  Ka-Leung Wonga  

* Corresponding authors

a Department of Chemistry, Durham University, South Road, Durham, UK
E-mail: david.parker@durham.ac.uk

Abstract

A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (ϕem 12%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.

Graphical abstract: Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B920222F
Article type
Communication
Submitted
29 Sep 2009
Accepted
20 Oct 2009
First published
02 Nov 2009

Chem. Commun., 2009, 7321-7323

Permissions

Request permissions

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

G. Law, R. Pal, L. O. Palsson, D. Parker and K. Wong, Chem. Commun., 2009, 7321 DOI: 10.1039/B920222F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements