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Dalton Transactions

The international journal for inorganic, organometallic and bioinorganic chemistry



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Dalton Trans., 2008, 6117 - 6120, DOI: 10.1039/b811224j


Zn(II) ions bind very efficiently to tandem repeat region of prion related protein (PrP-rel-2) of zebra-fish. MS and potentiometric evidence

Lukasz Szyrwiel, Elzbieta Jankowska, Anna Janicka-Klos, Zbigniew Szewczuk, Daniela Valensin and Henryk Kozlowski


Multi-histidine peptide fragments of zebra-fish prion protein are effective ligands for Zn(II) ions. Moreover the formation of a dinuclear complex species with a longer peptide can suggest the existence of the cooperative effect in the metal ion binding.

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