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Dalton Transactions

The international journal for inorganic, organometallic and bioinorganic chemistry



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Dalton Trans., 2008, 5293 - 5295, DOI: 10.1039/b812244j


Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

Olivia R. Allen, Richard J. Knox and Patrick C. McGowan


New neutral and ionic functionalised zirconocene dichloride compounds have been isolated and characterised. The ionic zirconocene exhibits excellent cytotoxicity against a range of human tumour cell lines, which represents the first active anticancer zirconocene dichloride compound.

Graphical abstract image for this article  (ID: b812244j)