Issue 4, 2009
From the journal:

Green Chemistry

Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

Louise Carson,a   Peter K. W. Chau,a   Martyn J. Earle,b   Manuela A. Gilea,b   Brendan F. Gilmore,*a   Sean P. Gorman,a   Maureen T. McCanna  and  Kenneth R. Seddonb  

* Corresponding authors

a School of Pharmacy, The Queens University of Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, UK
E-mail: b.gilmore@qub.ac.uk
Fax: +44 (0) 28 90 247 794
Tel: +44 (0) 28 90 972 047

b The QUILL Research Centre, School of Chemistry, The Queen's University of Belfast, Belfast, UK

Abstract

Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

Graphical abstract: Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

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Article information

DOI
https://doi.org/10.1039/B821842K
Article type
Paper
Submitted
05 Dec 2008
Accepted
22 Jan 2009
First published
18 Feb 2009

Green Chem., 2009,11, 492-497

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Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

L. Carson, P. K. W. Chau, M. J. Earle, M. A. Gilea, B. F. Gilmore, S. P. Gorman, M. T. McCann and K. R. Seddon, Green Chem., 2009, 11, 492 DOI: 10.1039/B821842K

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