Issue 32, 2007
From the journal:

Journal of Materials Chemistry

Current strategies towards hemocompatible coatings

Carsten Werner,*ab   Manfred F. Maitza  and  Claudia Sperlinga  

* Corresponding authors

a Max Bergmann Center of Biomaterials Dresden, Leibniz Institute of Polymer Research Dresden, Hohe Str. 6, 01069 Dresden
E-mail: werner@ipfdd.de
Fax: +49-351-4653-533
Tel: +49-351-4658-532

b University of Toronto, Institute of Biomaterials and Biomedical Engineering, Toronto, Canada

Abstract

A wide range of biomedical devices is applied clinically in contact with blood. Tailoring the surface properties of the involved biomaterials is a common approach to enhance performance and to limit adverse reactions. This review summarizes current trends in coating technologies developed for that purpose. Inorganic coatings were shown to substantially improve the durability and inertness of biomaterials while a number of advanced polymer coatings were demonstrated to be very effective by targeting specific biochemical pathways. However, to fully utilize the power of these bioactive coatings safety issues need to be thoroughly addressed in future studies.

Graphical abstract: Current strategies towards hemocompatible coatings

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Article information

DOI
https://doi.org/10.1039/B703416B
Article type
Application
Submitted
06 Mar 2007
Accepted
06 Jun 2007
First published
27 Jun 2007

J. Mater. Chem., 2007,17, 3376-3384

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Current strategies towards hemocompatible coatings

C. Werner, M. F. Maitz and C. Sperling, J. Mater. Chem., 2007, 17, 3376 DOI: 10.1039/B703416B

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