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Lab on a Chip

Microfluidic & nanofluidic technologies for chemistry, physics, biology, and bioengineering




Communication

Lab Chip, 2009, 9, 2764 - 2766, DOI: 10.1039/b910703g


Automated high-throughput cell microsurgery on-chip

Kwanghun Chung and Hang Lu


Laser cell kill is an established tool for studying cells' roles during development and behavior, but its use has been limited due to the manual and low-throughput nature. We demonstrate here a technique combining multiplexing microfluidic manipulation of Caenorhabditis elegans and software for image processing and automation, allowing for high-throughput cell ablations.

Graphical abstract image for this article  (ID: b910703g)