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Previous news from Metallomics
Contents list for Metallomics, issue 2, 2010
Front cover
Metallomics, 2010, 2, 93
DOI: 10.1039/c001750g

Inside front cover
Metallomics, 2010, 2, 94
DOI: 10.1039/c001753c
Contents
Metallomics, 2010, 2, 95
DOI: 10.1039/c001756f
Editorials
Metallomics scope
Metallomics, 2010, 2, 102
DOI: 10.1039/c001365j

2009 International Symposium on Metallomics
Metallomics, 2010, 2, 103
DOI: 10.1039/c001179g

This themed issue of Metallomics captures just a little of what you might have missed in Cincinnati.
Perspective
Bioimaging of metals in brain tissue by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and metallomics
J. Sabine Becker, Andreas Matusch, Christoph Palm, Dagmar Salber, Kathryn A. Morton and J. Susanne Becker,
Metallomics, 2010, 2, 104
DOI: 10.1039/b916722f
Enhanced HTML article available

Novel LA-ICP-MS bioimaging techniques have been established for quantitative distribution analysis of elements in clinical specimens at routine scales and were combined with metallomic studies by biomolecular analytical tools.
Tutorial Reviews
Targeting selenium metabolism and selenoproteins: Novel avenues for drug discovery
Sarah Elizabeth Jackson-Rosario and William Thomas Self,
Metallomics, 2010, 2, 112
DOI: 10.1039/b917141j
Enhanced HTML article available

Recent discoveries in bioinorganic chemistry and selenoprotein enzymology suggest that targeting of specific selenoproteins, or the metabolism of selenium, can be a rich avenue for drug discovery.
Metalloproteomics, metalloproteomes, and the annotation of metalloproteins
Wolfgang Maret,
Metallomics, 2010, 2, 117
DOI: 10.1039/b915804a
Enhanced HTML article available

How metalloproteins select the correct metal ion needs to be addressed in the context of the metal homeostatic systems and the ecology of an organism.
Papers
Dynamic pathways of selenium metabolism and excretion in mice under different selenium nutritional statuses
Yoshinari Suzuki, Yoshiteru Hashiura, Kentaro Matsumura, Takahisa Matsukawa, Atsuko Shinohara and Naoki Furuta,
Metallomics, 2010, 2, 126
DOI: 10.1039/b915816b

Time-dependent changes of exogenous and endogenous 82Se associated with cellular glutathione peroxidase (cGPx) in liver and kidney were investigated.
A proteome investigation of roxarsone degradation by Alkaliphilus oremlandii strain OhILAs
Peter Chovanec, John F. Stolz and Partha Basu,
Metallomics, 2010, 2, 133
DOI: 10.1039/b915479e
Enhanced HTML article available

Proteomic investigation of anaerobic bacterial degradation of an organoarsenical suggests the involvement of a molybdoenzyme.
Ribonucleoside labeling with Os(VI): A methodological approach to evaluation of RNA methylation by HPLC-ICP-MS
Katarzyna Wrobel, Crescencio Rodríguez Flores, Qilin Chan and Kazimierz Wrobel,
Metallomics, 2010, 2, 140
DOI: 10.1039/b915474d
Enhanced HTML article available

Labeling ribonucleosides with Os(VI) and their quantification by HPLC-ICP-MS is proposed as a new analytical strategy for the evaluation of RNA methylation.
Selenium speciation profiles in selenite-enriched soybean (Glycine Max) by HPLC-ICPMS and ESI-ITMS
Qilin Chan, Scott E. Afton and Joseph A. Caruso,
Metallomics, 2010, 2, 147
DOI: 10.1039/b916194e
Enhanced HTML article available

The bean of the soybean plant can accumulate significant amounts of Se, 82%, of which is high molecular weight Se and the remaining is mainly selenomethionine and selenocystine.
Simultaneous multiple element detection by particle beam/hollow cathode-optical emission spectroscopy as a tool for metallomic studies: Determinations of metal binding with apo-transferrin
C. Derrick Quarles, Jr., Julia L. Brumaghim and R. Kenneth Marcus,
Metallomics, 2010, 2, 154
DOI: 10.1039/b916073f
Enhanced HTML article available

PB/HC-OES is demonstrated to be an effective means to study the metal loading of apo-transferrin in single-element and competitive binding situations, providing high elemental specificity and sub-micromolar protein sensitivity.
In vivo bioavailability of selenium in enriched Pleurotus ostreatus mushrooms
Marliane C. S. da Silva, Juliana Naozuka, Pedro V. Oliveira, Maria C. D. Vanetti, Denise M. S. Bazzolli, Neuza M. B. Costa and Maria C. M. Kasuya,
Metallomics, 2010, 2, 162
DOI: 10.1039/b915780h
Enhanced HTML article available

The addition of Se-enriched mushrooms in the conventional diets of rats can result in the availability of Se for absorption and use in the biological functions of rats.
Formation of methylselenol, dimethylselenide and dimethyldiselenide in in vitro metabolism models determined by headspace GC-MS
Charlotte Gabel-Jensen, Kristoffer Lunře and Bente Gammelgaard,
Metallomics, 2010, 2, 167
DOI: 10.1039/b914255j

The aim of this study was to identify the presence of MeSeH in metabolic reactions. MeSeH was only detected in reducing environments and was readily oxidized to DMeDSe. The production of DMeDSe was demonstrated to proceed via the MeSeH intermediate.
Back matter
Metallomics, 2010, 2, 174
DOI: 10.1039/c001758m
Back cover
Metallomics, 2010, 2, 175
DOI: 10.1039/c001761m




