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Natural Product Reports

A critical review journal which stimulates progress in all areas of natural products research.



NPR Vitamins and Cofactors themed issue


27 September 2007

It has been known for over a century that substances other than proteins, fats, sugars and minerals are necessary in small amounts in the human diet. These organic compounds - vitamins - have been intensely studied ever since. 

This themed issue of Natural Product Reports, guest edited by Alison Smith and Finian Leeper from the University of Cambridge, UK, brings together six reviews which take different aspects of research into the chemistry, biochemistry and biology of vitamins and cofactors and show how, for each aspect, there are common themes for many of the pathways. 

on the front cover of issue 5

Cover image provided by Alison Smith (University of Cambridge, UK) and Michael Webb (University of Leeds, UK)


This issue also contains a Highlight article by Steven Weinreb from Pennsylvania State University, US, and six other reviews. 

Themed Content

Editorial: Vitamins and cofactors—chemistry, biochemistry and biology
Nat. Prod. Rep., 2007, 24, 923
DOI: 10.1039/b712088p

Roles of vitamins B5, B8, B9, B12 and molybdenum cofactor at cellular and organismal levels
Fabrice Rébeillé, Stéphane Ravanel, Andrée Marquet, Ralf R. Mendel, Alison G. Smith and Martin J. Warren, Nat. Prod. Rep., 2007, 24, 949
DOI: 10.1039/b703104c

Metal and cofactor insertion
Ralf R. Mendel, Alison G. Smith, Andree Marquet and Martin J. Warren, Nat. Prod. Rep., 2007, 24, 963
DOI: 10.1039/b703112m

Evolution of enzymes and pathways for the biosynthesis of cofactors
Gemma L. Holliday, Janet M. Thornton, Andrée Marquet, Alison G. Smith, Fabrice Rébeillé, Ralf Mendel, Heidi L. Schubert, Andrew D. Lawrence and Martin J. Warren, Nat. Prod. Rep., 2007, 24, 972
DOI: 10.1039/b703107f

Elucidating biosynthetic pathways for vitamins and cofactors
Michael E. Webb, Andrée Marquet, Ralf R. Mendel, Fabrice Rébeillé and Alison G. Smith, Nat. Prod. Rep., 2007, 24, 988
DOI: 10.1039/b703105j

Coenzyme biosynthesis: enzyme mechanism, structure and inhibition
Duncan E. Scott, Alessio Ciulli and Chris Abell, Nat. Prod. Rep., 2007, 24, 1009
DOI: 10.1039/b703108b

Coenzyme biosynthesis: enzyme mechanism, structure and inhibition
Duncan E. Scott, Alessio Ciulli and Chris Abell, Nat. Prod. Rep., 2007, 24, 1009
DOI: 10.1039/b703108b

Issue 5

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