The latest issue of Natural Product Reports is now available online.

In this issue, Tim Stinear and colleagues' Highlight article explores the structural diversity, biological activity, mode of action and biosynthesis of micolactones. Also available are five review articles on topics including biosilicifying organisms, natural products isolation and natural products-derived compounds in clinical trials. 

The front cover for this issue shows silica which has been formed enzymatically by the glass sponge Euplectella.