Issue 5, 2007
From the journal:

Natural Product Reports

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

Stefano Donadio,*a   Paolo Monciardinia  and  Margherita Sosioa  

* Corresponding authors

a KtedoGen, via Fantoli 16/15, 20132 Milan, Italy
E-mail: stefano.donadio@ktedogen.com

Abstract

Covering: bacterial genome sequences to 2005 and post-genomic literature to June 2006

A total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of genes encoding modular polyketide synthases (PKS) and nonribosomal peptide synthetases (NRPS). We report on the distribution of these systems in different bacterial taxa and, whenever known, the metabolites they synthesize. We also highlight, in the different bacterial lineages, the PKS and NRPS genes and, whenever known, the corresponding products.

Graphical abstract: Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B514050C
Article type
Review Article
Submitted
27 Feb 2007
First published
10 May 2007

Nat. Prod. Rep., 2007,24, 1073-1109

Permissions

Request permissions

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

S. Donadio, P. Monciardini and M. Sosio, Nat. Prod. Rep., 2007, 24, 1073 DOI: 10.1039/B514050C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements