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Highlight

Nat. Prod. Rep., 2009, 26, 865 - 873, DOI: 10.1039/b906991g

Synthesis and stereochemical determination of the spirastrellolides

Ian Paterson and Stephen M. Dalby

This Highlight summarises synthetic efforts towards the marine sponge-derived antimitotic agent spirastrellolide A and its congeners, including the first total synthesis by Paterson and co-workers.

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