Editorial 

Happy New Year to all Organic & Biomolecular Chemistry reviewers, authors and readers!  We are pleased to report that authors and readers alike agree that 2007 was a very successful year for Organic & Biomolecular Chemistry. 

 

Outside front cover 

In recent years a remarkable interest in bioorganometallics, such as metallo-nucleosides, has emerged. The cover focuses on the crystal structure of cobalt-modified 5-alkynyl-2'-deoxyuridine, which highlights the antitumour activity of hexacarbonyl dicobalt alkynes against breast cancer cells. 

 

Inside front cover and Emerging Area

Not much fits in between sheets of graphite, but there's enough room to accommodate nanometer clusters of nickel. And with reaction partners in the surrounding solution ready to couple as the sheets slide and eventually expose the metal, heterogeneous catalysis can occur to make either C-C or C-H bonds.

 

Perspective

Noncovalent bonding interactions between helical molecules show a tendency for pairs of the same configuration of the helicenes to form more stable complexes than pairs of enantiomeric helicenes.

 

Perpective

Thermal isomerizations through [1,3] carbon sigmatropic shifts take place through diradical intermediates, which also lead to fragmentations and epimerizations; orbital symmetry theory is not relevant.