RSC Publishing


Publishing

 

Cover image for Organic & Biomolecular Chemistry, click here for current issue

Organic & Biomolecular Chemistry

An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.




Issue 3 of OBC


25 January 2008

Outside front cover: 

Both enantiomers of 2-amino- 1-phenylethanol (2-APE) were resolved by the use of dehydroabietic acid (DAA), a natural chiral acid, by switching resolving solvents. The crystal structures of both diastereomeric salts, (R)-APE/DAA and (S)-APE/DAA, showed that EtOH molecule was only involved in (R)-APE/DAA to complete the necessary H-bond network.


 

Outside front cover for issue 3 2008 


Inside front and Emerging Area:

Conformationally rigid oligomers whose facially amphiphilic conformations can be exploited to generate a novel class of compounds that interacts with phospholipid bilayers and shows promise to be potent antimicrobial agents. 

 

Inside front cover for issue 3 2008



Perspective: 

In this article, Mathieu Pucheault aims to emphasize how natural products or engineered analogs can be used as chemical tools to apprehend some biological problems from the point of view of a chemical biologist.


 

Natural products that can be used as chemical tools to apprehend some biological problems.

 


Hot article: 

The stereoselective syntheses of 6-azauracil- and 8-aza-7-deazaadenine 2-deoxy-2'-fluoro-D-arabinofuranosides employing nucleobase anion glycosylation with 3,5-di-O-benzoyl-2-deoxy-2-fluoro- -D-arabinofuranosyl bromide 6 as the sugar component are described.

At pH 7.0 this compound forms a stable base pair with dT like that of dA.


References

Kayoko Taniguchi, Marie Aruga, Mikio Yasutake and Takuji Hirose, Org. Biomol. Chem., 2008, DOI:  10.1039/b717071h

Gregory J. Gabriel and Gregory N. Tew, Org. Biomol. Chem., 2008, DOI:  10.1039/b714490n 

Mathieu Pucheault,  Org. Biomol. Chem., 2008, DOI: 10.1039/b713022h

Frank Seela and Padmaja Chittepu,  Org. Biomol. Chem., 2008, DOI: 10.1039/b715512c

 

Organic & Biomolecular Chemistry Issue 3

View the contents of this issue

Read OBC's Emerging Areas

Short personal accounts of a new area of research.

Read OBC's Perspectives

Easy-to-read articles covering current areas of interest.