An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.
Issue 3 of OBC
25 January 2008
Outside front cover:
Both enantiomers of 2-amino- 1-phenylethanol (2-APE) were resolved by the use of dehydroabietic acid (DAA), a natural chiral acid, by switching resolving solvents. The crystal structures of both diastereomeric salts, (R)-APE/DAA and (S)-APE/DAA, showed that EtOH molecule was only involved in (R)-APE/DAA to complete the necessary H-bond network.
Inside front and Emerging Area:
Conformationally rigid oligomers whose facially amphiphilic conformations can be exploited to generate a novel class of compounds that interacts with phospholipid bilayers and shows promise to be potent antimicrobial agents.

Perspective:
In this article, Mathieu Pucheault aims to emphasize how natural products or engineered analogs can be used as chemical tools to apprehend some biological problems from the point of view of a chemical biologist.

Hot article:
The stereoselective syntheses of 6-azauracil- and 8-aza-7-deazaadenine 2-deoxy-2'-fluoro-D-arabinofuranosides employing nucleobase anion glycosylation with 3,5-di-O-benzoyl-2-deoxy-2-fluoro-
-D-arabinofuranosyl bromide 6 as the sugar component are described.

References
Kayoko Taniguchi, Marie Aruga, Mikio Yasutake and Takuji Hirose, Org. Biomol. Chem., 2008, DOI: 10.1039/b717071h
Gregory J. Gabriel and Gregory N. Tew, Org. Biomol. Chem., 2008, DOI: 10.1039/b714490n
Mathieu Pucheault, Org. Biomol. Chem., 2008, DOI: 10.1039/b713022h
Frank Seela and Padmaja Chittepu, Org. Biomol. Chem., 2008, DOI: 10.1039/b715512c
Organic & Biomolecular Chemistry Issue 3
View the contents of this issue
Short personal accounts of a new area of research.
Easy-to-read articles covering current areas of interest.
