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An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.
On the Front Cover of issue 18
The complex Pd(N,N-dimethylbenzylamine)(pyridine)(trifluoromethanesulfonate) shown in the ORTEP background on the cover is extremely effective for catalytic methanolysis of P=S pesticides. The active form shown as the space-filling model is one having an PdII-coordinated methoxide generated with a pKa of 10.8. This system promotes the turnover methanolysis of excess fenitrothion, diazinon, quinalphos, coumaphos and dichlofenthion at 25 ēC. An associative mechanism is proposed where the PdII-coordinated methoxide intramolecularly attacks a transiently coordinated S=P substrate.
Image reproduced by permission of R Stan Brown and Alexei Neverov |
An ortho-palladated dimethylbenzylamine complex as a highly efficient turnover catalyst for the decomposition of P
S insecticides. Mechanistic studies of the methanolysis of some PS-containing phosphorothioate triesters
Zhong-Lin Lu, Alexei A. Neverov and R. Stan Brown, Org. Biomol. Chem., 2005, 3, 3379
DOI: 10.1039/b508917d
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