An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.

The role of chemical synthesis in structure elucidation of oxasqualenoids
Yoshiki Morimoto, Org. Biomol. Chem., 2008, 6, 1709
DOI: 10.1039/b801126e

The synthesis of enantiomerically pure [2.2]paracyclophane derivatives
Gareth J. Rowlands, Org. Biomol. Chem., 2008, 6, 1527
DOI: 10.1039/b800698a

Frustrated Lewis pairs: a concept for new reactivity and catalysis
Douglas W. Stephan, Org. Biomol. Chem., 2008, 6, 1535
DOI: 10.1039/b802575b

Recent advances in enantioselective [2 + 2 + 2] cycloaddition
Takanori Shibata and Kyoji Tsuchikama, Org. Biomol. Chem., 2008, 6, 1317
DOI: 10.1039/b720031e

Molecular dipole engineering: new aspects of molecular dipoles in molecular architecture and their functions
Shunsaku Kimura, Org. Biomol. Chem., 2008, 6, 1143
DOI: 10.1039/b717898k

PET (positron emission tomography) imaging of biomolecules using metal–DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics
Katsunori Tanaka and Koichi Fukase, Org. Biomol. Chem., 2008, 6, 815
DOI: 10.1039/b718157b

Is vanadium a more versatile target in the activity of primordial life forms than hitherto anticipated?
Dieter Rehder, Org. Biomol. Chem., 2008, 6, 957
DOI: 10.1039/b717565p

Syntheses of manzacidins: a stage for the demonstration of synthetic methodologies
Takuya Hashimoto and Keiji Maruoka, Org. Biomol. Chem., 2008, 6, 829
DOI: 10.1039/b716062c

A hitchhiker's guide to G-quadruplex ligands
David Monchaud and Marie-Paule Teulade-Fichou, Org. Biomol. Chem., 2008, 6, 627
DOI: 10.1039/b714772b

Conformationally rigid proteomimetics: a case study in designing antimicrobial aryl oligomers
Gregory J. Gabriel and Gregory N. Tew, Org. Biomol. Chem., 2008, 6, 417
DOI: 10.1039/b714490n

Dynamic combinatorial chemistry: on the road to fulfilling the promise
Sylvain Ladame, Org. Biomol. Chem., 2008, 6, 219
DOI: 10.1039/b714599c

Heterogeneous catalysis with nickel-on-graphite (Ni/C_g)
Tom A. Butler, Elizabeth C. Swift and Bruce H. Lipshutz, Org. Biomol. Chem., 2008, 6, 19
DOI: 10.1039/b714600k

2007

The development of yoctowells as a basis for modeling biological systems
Sheshanath V. Bhosale and Steven J. Langford, Org. Biomol. Chem., 2007, 5, 3733
DOI: 10.1039/b712821e

Catalytic enantioselective stereoablative reactions: an unexploited approach to enantioselective catalysis
Justin T. Mohr, David C. Ebner and Brian M. Stoltz, Org. Biomol. Chem., 2007, 5, 3571
DOI: 10.1039/b711159m

Engineering proteins with tailored nanomechanical properties: a single molecule approach
Hongbin Li, Org. Biomol. Chem., 2007, 5, 3399
DOI: 10.1039/b710321m

Molecularly imprinted polymers (MIPs): sensing, an explosive new opportunity?
Adam McCluskey, Clovia I. Holdsworth and Michael C. Bowyer, Org. Biomol. Chem., 2007, 5, 3233
DOI: 10.1039/b708660a

-Amino acid-containing hybrid peptides—new opportunities in peptidomimetics
Marie-Isabel Aguilar, Anthony W. Purcell, Romila Devi, Rebecca Lew, Jamie Rossjohn, A. Ian Smith and Patrick Perlmutter, Org. Biomol. Chem., 2007, 5, 2884
DOI: 10.1039/b708507a

Palladium catalyzed arylation for the synthesis of polyarenes
Sergio Pascual, Paula de Mendoza and Antonio M. Echavarren, Org. Biomol. Chem., 2007, 5, 2727
DOI: 10.1039/b707940k

Nanoparticles and cells: good companions and doomed partnerships
Dusica Maysinger, Org. Biomol. Chem., 2007, 5, 2335
DOI: 10.1039/b704275b

Synthesis and properties of the chiral oligonaphthalenes
Kazunori Tsubaki, Org. Biomol. Chem., 2007, 5, 2179
DOI: 10.1039/b703558f

Recent advances in the formation of luminescent lanthanide architectures and self-assemblies from structurally defined ligands
Thorfinnur Gunnlaugsson and Floriana Stomeo, Org. Biomol. Chem., 2007, 5, 1999
DOI: 10.1039/b700232g

Pilicides—small molecules targeting bacterial virulence
Veronica Åberg and Fredrik Almqvist, Org. Biomol. Chem., 2007, 5, 1827
DOI: 10.1039/b702397a

Molecular rotors—fluorescent biosensors for viscosity and flow
Mark A. Haidekker and Emmanuel A. Theodorakis, Org. Biomol. Chem., 2007, 5, 1669
DOI: 10.1039/b618415d

The synthesis of chromenes, chromanes, coumarins and related heterocycles via tandem reactions of salicylic aldehydes or salicylic imines with ,-unsaturated compounds
Yong-Ling Shi and Min Shi, Org. Biomol. Chem., 2007, 5, 1499
DOI: 10.1039/b618984a

DNA meets synthetic polymers—highly versatile hybrid materials
Fikri E. Alemdaroglu and Andreas Herrmann, Org. Biomol. Chem., 2007, 5, 1311
DOI: 10.1039/b617941j

Microwave energy: a versatile tool for the biosciences
Jonathan M. Collins and Nicholas E. Leadbeater, Org. Biomol. Chem., 2007, 5, 1141
DOI: 10.1039/b617084f

Chiral dipeptide mimics possessing a fluoroolefin moiety: a relevant tool for conformational and medicinal studies
Samuel Couve-Bonnaire, Dominique Cahard and Xavier Pannecoucke, Org. Biomol. Chem., 2007, 5, 1151
DOI: 10.1039/b701559c

Photochemical control of biological processes
Douglas D. Young and Alexander Deiters, Org. Biomol. Chem., 2007, 5, 999
DOI: 10.1039/b616410m

Carbohydrate post-glycosylational modifications
Hai Yu and Xi Chen, Org. Biomol. Chem., 2007, 5, 865
DOI: 10.1039/b700034k

Micro reactors: a new tool for the synthetic chemist
Paul Watts and Charlotte Wiles, Org. Biomol. Chem., 2007, 5, 727
DOI: 10.1039/b617327f

Advanced organic synthesis using microreactor technology
Batoul Ahmed-Omer, Johan C. Brandt and Thomas Wirth, Org. Biomol. Chem., 2007, 5, 733
DOI: 10.1039/b615072a

Approaches to high throughput physical organic chemistry
Christophe Portal and Mark Bradley, Org. Biomol. Chem., 2007, 5, 587
DOI: 10.1039/b614923e

Molecular springs, muscles, rheostats, and precessing gyroscopes: from review to preview
Michael J. Marsella, Shohreh Rahbarnia and Nathan Wilmot, Org. Biomol. Chem., 2007, 5, 391
DOI: 10.1039/b613891h

Self-assembled multivalent carbohydrate ligands
Yong-beom Lim and Myongsoo Lee, Org. Biomol. Chem., 2007, 5, 401
DOI: 10.1039/b615744k

A systems perspective to digital structures in molecular analysis
Peyman Najmabadi, James J. La Clair and Michael D. Burkart, Org. Biomol. Chem., 2007, 5, 214
DOI: 10.1039/b614507h

Synthesis of protein–polymer conjugates
Karina L. Heredia and Heather D. Maynard, Org. Biomol. Chem., 2007, 5, 45
DOI: 10.1039/b612355d

2006

-Chelation-directed C–H functionalizations using Pd(II) and Cu(II) catalysts: regioselectivity, stereoselectivity and catalytic turnover
Jin-Quan Yu, Ramesh Giri and Xiao Chen, Org. Biomol. Chem., 2006, 4, 4041
DOI: 10.1039/b611094k

DNA-based machines
Moritz K. Beissenhirtz and Itamar Willner, Org. Biomol. Chem., 2006, 4, 3392
DOI: 10.1039/b607033g

Synthetic functional -stack architecture in lipid bilayers
Sheshanath Bhosale, Adam L. Sisson, Naomi Sakai and Stefan Matile, Org. Biomol. Chem., 2006, 4, 3031
DOI: 10.1039/b606487f

Stereochemical relays: communication via conformation
Jonathan Clayden and Neoclis Vassiliou, Org. Biomol. Chem., 2006, 4, 2667
DOI: 10.1039/b604548k

Unlocking the potential of thiaheterohelicenes: chemical synthesis as the key
Shawn K. Collins and Martin P. Vachon, Org. Biomol. Chem., 2006, 4, 2518
DOI: 10.1039/b603305a

Daucus carota L. mediated bioreduction of prochiral ketones
Nicolas Blanchard and Pierre van de Weghe, Org. Biomol. Chem., 2006, 4, 2348
DOI: 10.1039/b605233a

Syntheses of polysubstituted furans: recent developments
Stefan F. Kirsch, Org. Biomol. Chem., 2006, 4, 2076
DOI: 10.1039/b602596j

Interception of quorum sensing in Staphylococcus aureus: a new niche for peptidomimetics
Benjamin C. Gorske and Helen E. Blackwell, Org. Biomol. Chem., 2006, 4, 1441
DOI: 10.1039/b517681f

Electrophilic fluorination of organosilanes
Matthew Tredwell and Véronique Gouverneur, Org. Biomol. Chem., 2006, 4, 26
DOI: 10.1039/b513399h

2005

Asymmetric hydrogenation of aromatic compounds
Frank Glorius, Org. Biomol. Chem., 2005, 3, 4171
DOI: 10.1039/b512139f

Directing the secondary structure of polypeptides at will: from helices to amyloids and back again?
Kevin Pagel, Toni Vagt and Beate Koksch, Org. Biomol. Chem., 2005, 3, 3843
DOI: 10.1039/b510098d

Synthetic mimics of mammalian cell surface receptors: prosthetic molecules that augment living cells
Blake R. Peterson, Org. Biomol. Chem., 2005, 3, 3607
DOI: 10.1039/b509866a

One-pot multi-step synthesis: a challenge spawning innovation
Steven J. Broadwater, Shoshannah L. Roth, Kristin E. Price, Muris Kobalija and D. Tyler McQuade, Org. Biomol. Chem., 2005, 3, 2899
DOI: 10.1039/b506621m

Recent experimental and theoretical developments towards the observation of parity violation (PV) effects in molecules by spectroscopy
Jeanne Crassous, Christian Chardonnet, Trond Saue and Peter Schwerdtfeger, Org. Biomol. Chem., 2005, 3, 2218
DOI: 10.1039/b504212g

Catalytic asymmetric hydroamination of non-activated olefins
Kai C. Hultzsch, Org. Biomol. Chem., 2005, 3, 1819
DOI: 10.1039/b418521h

Synthesis of technomimetic molecules: towards rotation control in single-molecular machines and motors
Gwénaël Rapenne, Org. Biomol. Chem., 2005, 3, 1165
DOI: 10.1039/b419282f

Asymmetric organocatalysis
Jayasree Seayad and Benjamin List, Org. Biomol. Chem., 2005, 3, 719
DOI: 10.1039/b415217b

The golden gate to catalysis
Anja Hoffmann-Röder and Norbert Krause, Org. Biomol. Chem., 2005, 3, 387
DOI: 10.1039/b416516k

New chiral anion mediated asymmetric chemistry
Jérôme Lacour and Richard Frantz, Org. Biomol. Chem., 2005, 3, 15
DOI: 10.1039/b413554g

2004

Deoxyribozymes: DNA catalysts for bioorganic chemistry
Scott K. Silverman, Org. Biomol. Chem., 2004, 2, 2701
DOI: 10.1039/B411910J

The renaissance of palladium(II)-catalyzed oxidation chemistry
Matthew S. Sigman and Mitchell J. Schultz, Org. Biomol. Chem., 2004, 2, 2551
DOI: 10.1039/B409127M

The RuO₄-catalysed dihydroxylation, ketohydroxylation and mono oxidation—novel oxidation reactions for the synthesis of diols and -hydroxy ketones
Bernd Plietker and Meike Niggemann, Org. Biomol. Chem., 2004, 2, 2403
DOI: 10.1039/B407937J

The sulfinic acid switch in proteins
Claus Jacob, Andrea L. Holme and Fiona H. Fry, Org. Biomol. Chem., 2004, 2, 1953
DOI: 10.1039/b406180b

The utility of indium in aqueous medium radical reactions
Hideto Miyabe and Takeaki Naito, Org. Biomol. Chem., 2004, 2, 1267
DOI: 10.1039/b316787a

Nucleic acid nanotechnology—towards Ångström-scale engineering
Jesper Wengel, Org. Biomol. Chem., 2004, 2, 277
DOI: 10.1039/b313986g

A molecular switchboard—covalent modifications to proteins and their impact on transcription
Nelly Khidekel and Linda C. Hsieh-Wilson, Org. Biomol. Chem., 2004, 2, 1
DOI: 10.1039/b312466e

2003

Directed evolution of enzymes: new biocatalysts for asymmetric synthesis
Marina Alexeeva, Reuben Carr and Nicholas J. Turner, Org. Biomol. Chem., 2003, 1, 4133
DOI: 10.1039/b311055a

Diversity-oriented synthesis; a challenge for synthetic chemists
David R. Spring, Org. Biomol. Chem., 2003, 1, 3867
DOI: 10.1039/b310752n

Chemical approaches to studying transcription
Ross V. Weatherman, Org. Biomol. Chem., 2003, 1, 3257
DOI: 10.1039/b307987b

The tethered aminohydroxylation (TA) reaction
Timothy J. Donohoe, Peter D. Johnson and Richard J. Pye, Org. Biomol. Chem., 2003, 1, 2025
DOI: 10.1039/b305189g

Regulating transcription: a chemical perspective
Anna K. Mapp, Org. Biomol. Chem., 2003, 1, 2217
DOI: 10.1039/b302656f

Out of the oil bath and into the oven—microwave-assisted combinatorial chemistry heats up
Helen E. Blackwell, Org. Biomol. Chem., 2003, 1, 1251
DOI: 10.1039/b301432k

Metabolic engineering—a genetic toolbox for small molecule organic synthesis
Org. Biomol. Chem., 2003, 1, 1
DOI: 10.1039/b210173d

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