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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.



OBC Hot Article Archive 2008



Hot Articles from 2008

Non-covalent delivery of proteins into mammalian cells
Aurore Loudet, Junyan Han, Rola Barhoumi, Jean-Philippe Pellois, Robert C. Burghardt and Kevin Burgess, Org. Biomol. Chem., 2008, 6, 4516
DOI: 10.1039/b809006h


Rapid typing of STRs in the human genome by HyBeacon® melting
Nittaya Gale, David J. French, Rebecca L. Howard, David G. McDowell, Paul G. Debenham and Tom Brown, Org. Biomol. Chem., 2008, 6, 4553
DOI: 10.1039/b813431f


Mechanistic approaches to palladium-catalyzed alkene difunctionalization reactions
Katrina H. Jensen and Matthew S. Sigman, Org. Biomol. Chem., 2008, 6, 4083
DOI: 10.1039/b813246a


Transannular rearrangement of activated 2,5-diketopiperazines: a key route to original scaffolds
Daniel Farran, Isabelle Parrot, Loïc Toupet, Jean Martinez and Georges Dewynter, Org. Biomol. Chem., 2008, 6, 3989
DOI: 10.1039/b810352f


Copper-free click: 1,3-dipolar cycloaddition of azides and arynes
Lachlan Campbell-Verduyn, Philip H. Elsinga, Leila Mirfeizi, Rudi A. Dierckx and Ben L. Feringa, Org. Biomol. Chem., 2008, 6, 3461
DOI: 10.1039/b812403e


Investigations into the effectiveness of deuterium as a protecting group for C–H bonds in radical reactions involving hydrogen atom transfer
Mark E. Wood, Sabine Bissiriou, Christopher Lowe and Kim M. Windeatt, Org. Biomol. Chem., 2008, 6, 3048
DOI: 10.1039/b810018g


Exploring the substrate specificity of OxyB, a phenol coupling P450 enzyme involved in vancomycin biosynthesis
Katharina Woithe, Nina Geib, Odile Meyer, Tanja Wörtz, Katja Zerbe and John A. Robinson, Org. Biomol. Chem., 2008, 6, 2861
DOI: 10.1039/b805956j


Bright molecules with sense, logic, numeracy and utility
A. Prasanna de Silva, Thomas P. Vance, Matthew E. S. West and Glenn D. Wright, Org. Biomol. Chem., 2008, 6, 2468
DOI: 10.1039/b802963f


Epigenetic remodeling of the fungal secondary metabolome
Russell B. Williams, Jon C. Henrikson, Ashley R. Hoover, Andrlynn E. Lee and Robert H. Cichewicz, Org. Biomol. Chem., 2008, 6, 1895
DOI: 10.1039/b804701d


The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design
Cristina Lucas-Lopez, John S. Allingham, Tomas Lebl, Christopher P. A. T. Lawson, Ruth Brenk, James R. Sellers, Ivan Rayment and Nicholas J. Westwood, Org. Biomol. Chem., 2008, 6, 2076
DOI: 10.1039/b801223g


A new approach to anodic substitution reaction using acoustic emulsification
Ryosuke Asami, Toshio Fuchigami and Mahito Atobe, Org. Biomol. Chem., 2008, 6, 1938
DOI: 10.1039/b802961j


Recent advances in enantioselective [2 + 2 + 2] cycloaddition
Takanori Shibata and Kyoji Tsuchikama, Org. Biomol. Chem., 2008, 6, 1317
DOI: 10.1039/b720031e


The role of chemical synthesis in structure elucidation of oxasqualenoids
Yoshiki Morimoto, Org. Biomol. Chem., 2008, 6, 1709
DOI: 10.1039/b801126e


Total synthesis of (-)-ulapualide A, a novel tris-oxazole macrolide from marine nudibranchs, based on some biosynthesis speculation
Gerald Pattenden, Neil J. Ashweek, Charles A. G. Baker-Glenn, James Kempson, Gary M. Walker and James G. K. Yee, Org. Biomol. Chem., 2008, 6, 1478
DOI: 10.1039/b801036f


Diversity-oriented synthesis; a spectrum of approaches and results
Richard J. Spandl, Andreas Bender and David R. Spring, Org. Biomol. Chem., 2008, 6, 1149
DOI: 10.1039/b719372f


Guest exchange in dimeric capsules formed by tetra-urea calix[4]arenes
Ivan Vatsouro, Ellen Alt, Myroslav Vysotsky and Volker Böhmer, Org. Biomol. Chem., 2008, 6, 998
DOI: 10.1039/b719053k