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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.




OBC news archive 2005


front cover of issue 24, 2005

On the front cover of Issue 24

John C Vederas reports the first stereoselective synthesis of aziridine analogues of diaminopimelic acid (DAP) and their evaluation as inhibitors of DAP epimerase


on the cover of issue 23

On the front cover of Issue 23

The cover of the latest issue of OBC illustrates the metal-mediated crystallization-induced dynamic resolution of acid with a cheap chiral acid (D-DBTA for example).


Issue 22 Cover

On the front cover of Issue 22

The cover of the latest issue of OBC shows how molecules, materials and complex DNA-structures are organized at the nanometer-scale by DNA-programmed self-assembly.


Issue 21 Cover

On the Front Cover of Issue 21

The cover of the issue 21 of OBC shows a tentative binding model between substituted 2-pyridones and the periplasmic chaperone PapD found in uropathogenic Escherichia coli.


Switching off neurodegenerative disease

Proof that peptide secondary structures can be switched by metal ions has been provided by a model based on a well known protein motif


issue 20 cover

On the Front Cover of Issue 20

The cover of the latest issue of OBC shows hydrogen-bonded double rosette nanoparticles "swimming" in water, reflecting their high stability in polar solvents.


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New RSS feeds for RSC journals

RSS feeds provide live updates of the latest articles direct to your PC, offering an effective way to browse journals online


Issue 19 outside front cover

On the Front Cover of Issue 19

Lucidene is a natural product isolated from the root bark of Uvaria lucidassp.


Issue 19 inside front cover

On the inside front cover of Issue 19

Hydraphiles are synthetic ion channels that function in synthetic liposomes.


OBC Cover Issue 18

On the Front Cover of issue 18

An Ortho-palladated Dimethylbenzylamine Complex as a Highly Efficient Turnover Catalyst for the Decomposition of P=S Insecticides.


The illustration provides a schematic representation of the anti-proliferative effect produced by an ester-linked conjugate between methotrexate, an antifolate cancer chemotherapeutic, and motexafin gadolinium, an experimental cancer agent demonstrating selective tumor localization.

On the inside front cover of issue 18

Gadolinium Texaphyrin-Methotrexate Conjugates. Towards Improved Cancer Chemotherapeutic Agents


OBC Cover Issue 17

On our Front Cover issue 17

Fast and flexible synthetic route to the branched tetrasaccharide structures present in many saponins, including the tomato glycoalkaloid a-tomatine.


Hot Paper in issue 17 - Tomatoes get defensive

Methyl lycotetraoside, the tetrasaccharide constituent of the tomato defence glycoalkaloid alpha-tomatine


Hot Paper in issue 17 - One-Pot Palladium Reactions

A New Reactivity Pattern for Vinyl Bromides; Cine-Substitution via Palladium Catalysed C-N Coupling/Michael Addition Reactions


Chinese cover PCCP Issue 14, 2005

Chemical Science in China

This month the RSC showcases work from China, in recognition of the growing importance of Chinese research in the Chemical Sciences


OBC Cover Issue 14

OBC focuses on Chemical Science in China

OBC showcases work from China in issue 14, in recognition of the growing importance of Chinese research in the Chemical Sciences


Switching off neurodegenerative disease

Proof that peptide secondary structures can be switched by metal ions has been provided by a model based on a well known protein motif


Borromean

Molecular Borromean rings unlocked

Chemists in the US have provided verification of the structure of their acclaimed nanoscale Borromean rings, and suggest that they can now find practical applications for the rings...


foldamer

Amide foldamer bites back

A polyamide that folds back on itself, biting its tail, to make a compact three dimensional structure has been stumbled across by researchers in the UK


Dye lights up chain reaction

An improved fluorescence quencher that can analyse the products of polymerase chain reactions (PCR) has been developed by researchers in the UK


Molecular bowl

A bowl-shaped supramolecular structure has been designed and made by scientists in China and Japan


basket

Arranging molecules in baskets to make rings

Basket-shaped molecules holding pre-organised molecules in place have helped German scientists to make huge ring compounds


OBC Cover Issue 16

On our front Cover this issue

One-pot multi-step synthesis: a challenge spawning innovation


Rock, Paper, Scissors is a decision making game played by substituting these 3 elements with hand signals. Rock beats scissors and loses to paper. Paper beats Rock and loses to scissors. Scissors beats paper and loses to rock. (All elements stalemate against themselves.)

On our Inside Front Cover this issue

Two-stage enzyme mediated drug release from LMWG hydrogels


OBC future looks bright

OBC is delighted to announce its new editor, Dr Vikki Allen, and its first ISI impact factor, 2.194.


Meet the OBC Editorial team

Take a look at what conferences the OBC Editorial team are attending this year and come and see us. We are looking forward to meeting you!


Photo-Footprinting

OBC author scores top ten hit!

A recent Organic & Biomolecular Chemistry paper by Steven Ley and team at the University of Cambridge, UK, is among the Chemical Abstracts Service ten most requested articles.


Read the first articles from Molecular BioSystems for free, today!

The first articles for Molecular BioSystems have now been published online as Advance Articles.



Hot Paper in this issue - Controlled Mutation to Make Drugs

Proposed mechanism for diterpene synthases in the formation of phomactatriene and taxadiene


Hot Paper - Controlling Peptide Turns

Synthesis of 5/7-, 5/8- and 5/9-bicyclic lactam templates as constraints for external -turns