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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.



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Org. Biomol. Chem., 2007, 5, 223 - 225, DOI: 10.1039/b615450f

Diagnosing viruses by the rolling circle amplified synthesis of DNAzymes

Zoya Cheglakov, Yossi Weizmann, Bernhard Basnar and Itamar Willner

Circular DNA is used as a template for the amplified detection of M13 phage ssDNA by a rolling circle amplification (RCA) process that synthesizes DNAzyme chains, thus enabling the colorimetric or chemiluminescent detection of the analyte.

Graphical abstract image for this article (ID: b615450f)