RSC Publishing


Publishing

 

Cover image for Organic & Biomolecular Chemistry, select for current issue

Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.



Subscribers

Non-subscribers

Free access



Paper

Org. Biomol. Chem., 2008, 6, 3059 - 3064, DOI: 10.1039/b806883f

Synthesis and in vitro evaluation of imidazole-based wakayin analogues

Hung Hoang, Xiaofen Huang and Edward B. Skibo

Analogues of wakayin based on diimidazo[1,5,4-de, 1,5,4-h]-quinoxaline have been prepared and evaluated with respect to cytostatic and cytotoxic activity. Assays in a 60-cell-line human cancer panel revealed selective activity against cells with the VEGF (Flt-1) receptor.

Graphical abstract image for this article (ID: b806883f)