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Org. Biomol. Chem., 2009, 7, 2247 - 2254, DOI: 10.1039/b902510n
New development of glycan arrays
Chung-Yi Wu, Pi-Hui Liang and Chi-Huey Wong
The development of glycan arrays has enabled the high-sensitivity and high-throughput analysis of carbohydrate–protein interactions and contributed to significant advances in glycomics. A number of new array platforms that allow for qualitative and quantitative analysis of mono- and multivalent interactions on surfaces have been developed recently. Glycan arrays are not only a powerful tool for basic research, but also a promising technique for medical diagnosis, and detection of pathogens and cancers. These studies also have led to the design of efficient carbohydrate-based antimicrobial or anticancer vaccines.
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