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Org. Biomol. Chem., 2009, 7, 2841 - 2847, DOI: 10.1039/b906445a
Recent highlights in the synthesis of highly functionalized pyrimidines
Marco Radi, Silvia Schenone and Maurizio Botta
The pyrimidine scaffold represents an important pharmacophore endowed with a wide range of pharmacological activities according to the specific decoration of the heterocycle. This perspective article will briefly outline the most interesting approaches recently reported for the synthesis of highly functionalized pyrimidine derivatives.
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