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Organic & Biomolecular Chemistry

An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.



Natural products research articles in Organic & Biomolecular Chemistry



Organic & Biomolecular Chemistry publishes many aspects of natural products research - both cutting-edge new work and insightful review articles. Read more about our latest articles below.

Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides
Panumart Thongyoo, Núria Roqué-Rosell, Robin J. Leatherbarrow and Edward W. Tate, Org. Biomol. Chem., 2008, 6, 1462
DOI: 10.1039/b801667d
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Total synthesis of (-)-ulapualide A, a novel tris-oxazole macrolide from marine nudibranchs, based on some biosynthesis speculation
Gerald Pattenden, Neil J. Ashweek, Charles A. G. Baker-Glenn, James Kempson, Gary M. Walker and James G. K. Yee, Org. Biomol. Chem., 2008, 6, 1478
DOI: 10.1039/b801036f
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Synthesis and bioactivity of the gibberellin, 18-hydroxy-GA1 (GA132)
Ellen Morrison, Peter M. Chandler, Regan J. Thomson and Lewis N. Mander, Org. Biomol. Chem., 2008, 6, 1416
DOI: 10.1039/b800728d
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Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues
Justin J. Richards, T. Eric Ballard and Christian Melander, Org. Biomol. Chem., 2008, 6, 1356
DOI: 10.1039/b719082d
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Diversity-oriented synthesis; a spectrum of approaches and results
Richard J. Spandl, Andreas Bender and David R. Spring, Org. Biomol. Chem., 2008, 6, 1149
DOI: 10.1039/b719372f
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Synthesis and biological activity of analogues of vanchrobactin, a siderophore from Vibrio anguillarum serotype O2
Raquel G. Soengas, Marta Larrosa, Miguel Balado, Jaime Rodríguez, Manuel L. Lemos and Carlos Jiménez, Org. Biomol. Chem., 2008, 6, 1278
DOI: 10.1039/b719713f
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Approach to the hyacinthacines: first non-chiral pool synthesis of (+)-hyacinthacine A1
P. Venkatram Reddy, Amaël Veyron, Peter Koos, Alexandre Bayle, Andrew E. Greene and Philippe Delair, Org. Biomol. Chem., 2008, 6, 1170
DOI: 10.1039/b800445e
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Synthesis of a common tetrasaccharide motif of Haemophilus influenzae LPS inner core structures
Karin Mannerstedt, Eva Segerstedt, Johan Olsson and Stefan Oscarson, Org. Biomol. Chem., 2008, 6, 1087
DOI: 10.1039/b717564g
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A novel efficient and versatile route to the synthesis of 5-O-feruloylquinic acids
Candice Menozzi Smarrito, Caroline Munari, Fabien Robert and Denis Barron, Org. Biomol. Chem., 2008, 6, 986
DOI: 10.1039/b719132d
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Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues
Bagher Amir-Heidari, Jenny Thirlway and Jason Micklefield, Org. Biomol. Chem., 2008, 6, 975
DOI: 10.1039/b718766c
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Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction
Fang Zheng and Chang-Guo Zhan, Org. Biomol. Chem., 2008, 6, 836
DOI: 10.1039/b716268e
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Probing the -1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants
Victoria A. Money, Alan Cartmell, Catarina I. P. D. Guerreiro, Valerie M.-A. Ducros, Carlos M. G. A. Fontes, Harry J. Gilbert and Gideon J. Davies, Org. Biomol. Chem., 2008, 6, 851
DOI: 10.1039/b719288f
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Activity and selectivity of W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus in organic solvents and ionic liquids: mono- and biphasic media
Musa M. Musa, Karla I. Ziegelmann-Fjeld, Claire Vieille and Robert S. Phillips, Org. Biomol. Chem., 2008, 6, 887
DOI: 10.1039/b717120j
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Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential
Marie A. Colucci, Gavin D. Couch and Christopher J. Moody, Org. Biomol. Chem., 2008, 6, 637
DOI: 10.1039/b715270a
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Efficient synthesis of (+)-1,8,8a-tri-epi-swainsonine, (+)-1,2-di-epi-lentiginosine, (+)-9a-epi-homocastanospermine and (-)-9-deoxy-9a-epi-homocastanospermine from a D-glucose-derived aziridine carboxylate, and study of their glycosidase inhibitory activities
K. S. Ajish Kumar, Vinod D. Chaudhari and Dilip D. Dhavale, Org. Biomol. Chem., 2008, 6, 703
DOI: 10.1039/b712753g
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Polycyclic framework synthesis of anominine and tubingensin A indole diterpenoids
Ben Bradshaw, Gorka Etxebarria-Jardí and Josep Bonjoch, Org. Biomol. Chem., 2008, 6, 772
DOI: 10.1039/b718280e
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Studies of nitrile oxide cycloadditions, and the phenolic oxidative coupling of vanillin aldoxime by Geobacillus sp. DDS012 from Italian rye grass silage
David R. Kelly, Simon C. Baker, David S. King, Deepa S. de Silva, Gwyn Lord and Jason P. Taylor, Org. Biomol. Chem., 2008, 6, 787
DOI: 10.1039/b716915a
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