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An international journal for the quickest publication of high-quality research covering the breadth of synthetic, physical and biomolecular organic chemistry.
Read more about OBC Hot Articles
Hot Paper: Bright future for functional molecules
07 May 2008
Molecules can display display logic, sense, numeracy and utility and communicate with humans using light signals.
Hot Paper: Fungi wake up to new natural products
29 April 2008
A ground-breaking method of getting fungi to produce normally 'hidden' compounds has been demonstrated by US scientists.
Hot Paper: Tuning chemical tools
24 April 2008
A combination of chemistry and biology is helping find new tools for protein research.
Hot Paper: Ultrasonic approach to forming carbon bonds
10 April 2008
Electrocatalysis helps overcome unwanted oxidation of nucleophiles
Hot Paper: Recent additions to chiral synthesis
31 March 2008
Strategies for enantioselective transition metal-catalysed cycloadditions are discussed.
Hot Paper: Chemical synthesis solves structures
25 March 2008
The stereostructures of three natural products are determined through chemical syntheses.
Hot Paper: Sea slug macrocycle synthesised
06 March 2008
The total synthesis of a complex natural product isolated from nudibranch eggmasses is reported.
Hot Paper: Diversity-oriented synthesis
27 February 2008
The varied molecular architectures present in Nature are mimicked by preparing skeletally diverse small molecules.
![tetra-urea calix[4]arenes](/images/thumbnail_tcm18-113883.jpg)
Hot Paper: New insight into guest exchange
20 February 2008
The rate of guest exchange in calixarene capsules depends on the size of the groups attached to the narrow rim.
Hot Paper: A new brew for coffee derivatives
13 February 2008
Scientists in Switzerland have optimised a novel synthesis of a polyphenolic compound found in coffee beans.
Hot Paper: Making sense of ROS
17 December 2007
Two new fluorescent sensors for reactive oxygen species are reported.
Hot Paper: PASSport to enzyme immobilisation
13 November 2007
A microreactor concept for immobilised enzymes is disclosed.
Hot Paper: Cavitand catalysis
05 November 2007
A deep cavitand catalyses the Diels-Alder reaction of bound maleimides.
![deuterium-labeled bicyclo[4.2.0]oct-2-ene](/images/Thumbnail_tcm18-104519.jpg)
Hot Paper: Atoms on the move
18 October 2007
US researchers investigate the mechanism of [1,3] carbon shifts.
Hot Paper: Bismuth catalysts for Mannich-type reactions
12 October 2007
Canadian researchers have developed an efficient bismuth-catalysed Mannich-type 3-component reaction.
Hot Paper: Radicals in a spin
02 October 2007
UK researchers investigate gold nanoparticle-initiated free radical oxidations and halogen abstractions.
Hot Paper: Peptides get knotted
01 August 2007
UK researchers report for the first time the in vitro maturation of a unique peptide knot.
Hot Paper: Cure for Chagas' disease a step closer
30 July 2007
Combining chemical and enzymatic approaches brings promise of a cure for a debilitating parasitic disease.
Hot Paper: Mixed-up inhibitors
25 April 2007
Dutch researchers have taken a mix-and-match approach to probing the proteasome.
Hot Paper: A new fluorescent probe for reactive oxygen species
04 April 2007
A new sensor that can efficiently monitor damaging reactive oxygen species (ROS) in biological samples has been developed.
Hot Article: Natural products inspire organometallic drugs
22 March 2007
Exploring the use of metal complexes in synthesising new molecular scaffolds and discovering new compounds.
Hot Paper: Shedding light on porphyrin problem
21 March 2007
Until now it was assumed that the rapid decay of fused porphyrin oligomers is due to the small energy gap, however new research shows that this is not the case.
Hot Paper: Lighting the way to larger peptides
06 February 2007
US Chemists have developed a photochemical approach to stitching together peptides and proteins.
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