Read more about OBC Hot Articles

Hot Article: borono-analogues of nucleotides
16 September 2009
Synthesis of borono-analogues of nucleotides
Hot Article: An unusual twist for functional assemblies
13 August 2009
An international team of researchers have stumbled across some unique coil-shaped nanostructures when investigating photoresponsive functional assemblies

Hot Article: Taking the strain off spiropentane synthesis
17 July 2009
US chemists have developed an easy, direct route to a class of small, strained organic molecules that could be used in drug discovery.
Hot Article: Investigating parasitic invasion
04 June 2009
Chemists have identified that peroxiredoxin II is inhibited by a molecule that stops parasitic invasion.

Hot Article: Chemoenzymatic synthesis of aszonalenin natural products
A highly selective one-step synthesis of natural products using enzymes to convert polycyclic precursors into aszonalenins
Hot Article: Base-catalysed coupling gets the green light
04 March 2009
Chemists have developed a solvent- and metal-free coupling reaction for creating carbon-carbon bonds
Hot Article: A better view of cell death
23 February 2009
A new class of radio-labelled compounds that can image dying cells could be used to show if drugs are effective at blocking or inducing cell death
Hot Article: Deciphering peptoid relationships
13 February 2009
Helen Blackwell and Sarah Fowler from the University of Wisconsin-Madison, US, focus on the relationship between peptoid structure and function
Hot Article: Breaking the mould with a clay catalyst
27 January 2009
Japanese chemists have combined a clay with a metal complex to make an effective catalyst for a selective organic reaction
Hot Article: X-ray marks the spot for prodrug
22 December 2008
Japanese scientists have made a radiation-triggered prodrug that could improve chemotherapy

Hot Article: Non-covalent delivery
02 December 2008
Scientists in the US develop non-covalent carriers with the potential to mediate the transport of proteins into cells
Hot Article: Coiled coil calls the shots
18 November 2008
German scientists use peptides and pH to control the organisation of nanoparticles

Forensic science hots up
31 October 2008
Could fluorescent probes offer DNA profiling at the scene of a crime?
Rings feel the squeeze
22 September 2008
French scientists have discovered an unprecedented ring contraction reaction that can be used as a key route to promising heterocyclic scaffolds

Seeking protection from radicals
03 September 2008
UK scientists investigate deuterium as a protecting group for C-H bonds during radical reactions.
Hot Paper: Bright future for functional molecules
07 May 2008
Molecules can display display logic, sense, numeracy and utility and communicate with humans using light signals.
Hot Paper: Fungi wake up to new natural products
29 April 2008
A ground-breaking method of getting fungi to produce normally 'hidden' compounds has been demonstrated by US scientists.
Hot Paper: Tuning chemical tools
24 April 2008
A combination of chemistry and biology is helping find new tools for protein research.
Hot Paper: Ultrasonic approach to forming carbon bonds
10 April 2008
Electrocatalysis helps overcome unwanted oxidation of nucleophiles
Hot Paper: Recent additions to chiral synthesis
31 March 2008
Strategies for enantioselective transition metal-catalysed cycloadditions are discussed.
Hot Paper: Chemical synthesis solves structures
25 March 2008
The stereostructures of three natural products are determined through chemical syntheses.
Hot Paper: Sea slug macrocycle synthesised
06 March 2008
The total synthesis of a complex natural product isolated from nudibranch eggmasses is reported.

Hot Paper: Diversity-oriented synthesis
27 February 2008
The varied molecular architectures present in Nature are mimicked by preparing skeletally diverse small molecules.
Hot Paper: New insight into guest exchange
20 February 2008
The rate of guest exchange in calixarene capsules depends on the size of the groups attached to the narrow rim.
Hot Paper: A new brew for coffee derivatives
13 February 2008
Scientists in Switzerland have optimised a novel synthesis of a polyphenolic compound found in coffee beans.

Hot Paper: Making sense of ROS
17 December 2007
Two new fluorescent sensors for reactive oxygen species are reported.

