Issue 9, 1989

A novel ring transformation of 5-carbamoyluracils into barbituric acids

Abstract

Heating of 5-thiocarbamoyl-(3) and 5-carbamoyl-3-methyl-1-phenyluracil derivatives (5) in ethanolic sodium ethoxide causes a novel ring transformation to give 5-anilinomethylene-4-thiobarbituric acid (2) and 5-anilinomethylenebarbituric acids (6), respectively.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1989, 1695-1697

A novel ring transformation of 5-carbamoyluracils into barbituric acids

K. Hirota, H. Sajiki, Y. Kitade and Y. Maki, J. Chem. Soc., Perkin Trans. 1, 1989, 1695 DOI: 10.1039/P19890001695

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