Section C reviews annual developments in physical chemistry and chemical physics research
Review
Annu. Rep. Prog. Chem., Sect. C: Phys. Chem., 2005, 101, 202 - 215, DOI: 10.1039/b408866m
7 Catalytic antibodies
Fujie Tanaka
Reaction-based selections and catalysis-based selections have allowed development of catalytic antibodies with high catalytic activities. Fluorogenic substrates for monitoring bond-forming reactions, which are useful for catalysis-based selections of catalytic antibodies, have been developed recently; substrates for monitoring of cleavage reactions have been employed for some time. Together with dissection of antibody-catalyzed reactions and structures of catalytic antibodies, development of strategies for selection of antibody catalysts with higher catalytic activities should provide desired catalytic antibodies with high catalytic activities.
RSS feed