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Soft Matter

Where physics meets chemistry meets biology for fundamental soft matter research.



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Soft Matter, 2006, 2, 190 - 204, DOI: 10.1039/b517354j

Engineering the nanoparticle–biomacromolecule interface

Chang-Cheng You, Ayush Verma and Vincent M. Rotello

Monolayer-protected nanoparticles feature tunable size, surface functionality and core material, providing scaffolds for targeting biomacromolecules. This review highlights recent advances in nanoparticle-biomacromolecule interactions, focusing on two key areas: (1) The modulation of structure and function of biomacromolecules through engineered interactions with nanoparticle surfaces; (2) The use of biomacromolecules as building blocks for nanostructured materials.

Graphical abstract image for this article (ID: b517354j)