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Where physics meets chemistry meets biology for fundamental soft matter research.
Review
Soft Matter, 2006, 2, 822 - 835, DOI: 10.1039/b607706d
Peptide-based stimuli-responsive biomaterials
Robert J. Mart, Rachel D. Osborne, Molly M. Stevens and Rein V. Ulijn
This article explores recent advances in the design and engineering of materials wholly or principally constructed from peptides. We focus on materials that are able to respond to changes in their environment (pH, ionic strength, temperature, light, oxidation/reduction state, presence of small molecules or the catalytic activity of enzymes) by altering their macromolecular structure. Such peptide-based responsive biomaterials have exciting prospects for a variety of biomedical and bionanotechnology applications in drug delivery, bio-sensing and regenerative medicine.
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