MedChemComm

2040-2503

Royal Society of Chemistry

Front cover

10.1039/c1md90045e

Author

Anonymous

2012

3 1 1 2

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MedChemComm

2040-2503

Royal Society of Chemistry

Contents list

10.1039/c1md90046c

Author

Anonymous

2012

3 1 3 10

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MedChemComm

2040-2503

Royal Society of Chemistry

Happy New Year from MedChemComm

10.1039/c1md90043a

Author

Anonymous

2012

3 1 11 12

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editorial

MedChemComm

2040-2503

Royal Society of Chemistry

European Federation for Medicinal Chemistry in partnership with MedChemComm

10.1039/c1md90044g

Author

Anonymous

2012

3 1 13 13

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editorial

MedChemComm

2040-2503

Royal Society of Chemistry

Polyamine-based small molecule epigenetic modulators

10.1039/c1md00220a

Sharma

Shiv K.

Hazeldine

Stuart

Crowley

Michael L.

Hanson

Allison

Beattie

Ross

Varghese

Sheeba

Senanayake

Thulani M. D.

Hirata

Aiko

Hirata

Fusao

Huang

Steinbergs

Nora

Murray-Stewart

Tracey

Bytheway

Ian

Casero

Robert A.

Woster

Patrick M.

2012

3 1 14 21

Abstract

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review-article

MedChemComm

2040-2503

Royal Society of Chemistry

Inhibitors of Stat5 protein signalling

10.1039/c1md00175b

Cumaraswamy

Abbarna A.

Todic

Aleksandra

Resetca

Diana

Minden

Mark D.

Gunning

Patrick T.

2012

3 1 22 27

Abstract

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review-article

MedChemComm

2040-2503

Royal Society of Chemistry

From the protein's perspective: the benefits and challenges of protein structure-based pharmacophore modeling

10.1039/c1md00210d

Sanders

Marijn P. A.

McGuire

Ross

Roumen

Luc

Esch

Iwan J. P. de

Vlieg

Jacob de

Klomp

Jan P. G.

Graaf

Chris de

2012

3 1 28 38

Abstract

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review-article

MedChemComm

2040-2503

Royal Society of Chemistry

The development of quinolone esters as novel antimalarial agents targeting the Plasmodium falciparum bc1 protein complex

10.1039/c1md00183c

Cowley

Robin

Leung

Suet

Fisher

Nicholas

Al-Helal

Mohammed

Berry

Neil G.

Lawrenson

Alexandre S.

Sharma

Raman

Shone

Alison E.

Ward

Stephen A.

Biagini

Giancarlo A.

O′Neill

Paul M.

2012

3 1 39 44

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Structure–activity relationships of methyl-lysine reader antagonists

10.1039/c1md00195g

Herold

J. Martin

James

Lindsey Ingerman

Korboukh

Victoria K.

Gao

Cen

Coil

Kaitlyn E.

Bua

Dennis J.

Norris

Jacqueline L.

Kireev

Dmitri B.

Brown

Peter J.

Jin

Jian

Janzen

William P.

Gozani

Frye

Stephen V.

2012

3 1 45 51

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Synthesis of chiral α-amino acid-derived 1H-1,2,4-triazoles and 1,2,4-triazines

10.1039/c1md00177a

Zadeh

Ebrahim H. Ghazvini

El-Gendy

Bahaa El-Dien M.

Pop

Alex G.

Katritzky

Alan R.

2012

3 1 52 55

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Non-iminosugar glucocerebrosidase small molecule chaperones

10.1039/c1md00200g

Marugan

Juan Jose

Huang

Wenwei

Motabar

Omid

Zheng

Wei

Xiao

Jingbo

Patnaik

Samarjit

Southall

Noel

Westbroek

Wendy

Lea

Wendy A.

Simeonov

Anton

Goldin

Ehud

DeBernardi

Maria A.

Sidransky

Ellen

2012

3 1 56 60

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Click JAHAs: conformationally restricted ferrocene-based histone deacetylase inhibitors

10.1039/c1md00203a

Spencer

John

Amin

Jahangir

Boddiboyena

Ramesh

Packham

Graham

Cavell

Breeze E.

Alwi

Sharifah S. Syed

Paranal

Ronald M.

Heightman

Tom D.

Wang

Minghua

Marsden

Brian

Coxhead

Peter

Guille

Matthew

Tizzard

Graham J.

Coles

Simon J.

Bradner.

James E.

2012

3 1 61 64

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Selective inhibition of E. coli 1-deoxy-d-xylulose-5-phosphate synthase by acetylphosphonates

10.1039/c1md00233c

Smith

Jessica M.

Vierling

Ryan J.

Meyers

Caren Freel

2012

3 1 65 67

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

A self-immolative dendritic glucuronide prodrug of doxorubicin

10.1039/c1md00193k

Grinda

Marion

Clarhaut

Jonathan

Renoux

Brigitte

Tranoy-Opalinski

Isabelle

Papot

Sébastien

2012

3 1 68 70

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Synthesis of hybrid 4-anilinoquinoline triazines as potent antimalarial agents, their in silico modeling and bioevaluation as Plasmodium falciparum transketolase and β-hematin inhibitors

10.1039/c1md00188d

Sharma

Moni

Chauhan

Kuldeep

Chauhan

Shikha S.

Kumar

Ashok

Singh

Shiv Vardan

Saxena

Jitendra K.

Agarwal

Pooja

Srivastava

Kumkum

Kumar

S. Raja

Puri

Sunil K.

Shah

Priyanka

Siddiqi

M. I.

Chauhan

Prem M. S.

2012

3 1 71 79

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

10.1039/c1md00225b

Mantri

Monica

Webby

Celia J.

Loik

Nikita D.

Hamed

Refaat B.

Nielsen

Michael L.

McDonough

Michael A.

McCullagh

James S. O.

Böttger

Angelika

Schofield

Christopher J.

Wolf

Alexander

2012

3 1 80 85

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini

10.1039/c1md00272d

Stach

Michaela

Maillard

Noélie

Kadam

Rameshwar U.

Kalbermatter

David

Meury

Marcel

Page

Malcolm G. P.

Fotiadis

Dimitrios

Darbre

Tamis

Reymond

Jean-Louis

2012

3 1 86 89

Abstract

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MedChemComm

2040-2503

Royal Society of Chemistry

Amidines bearing benzofuroxan or benzimidazole 1,3-dioxide core scaffolds as Trypanosoma cruzi-inhibitors: structural basis for their interactions with cruzipain

10.1039/c1md00223f

Merlino

Alicia

Benitez

Diego

Campillo

Nuria E.

Páez

Juan A.

Tinoco

Luzineide W.

González

Mercedes

Cerecetto

Hugo

2012

3 1 90 101

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

Synthesis, nano-features, ex vivo anti-platelet aggregation and in vivo antithrombotic activities of poly-α,β-dl-aspartyl-l-arginine

10.1039/c1md00222h

Gui

Lin

Zhao

Ming

Wang

Yuji

Wang

Yinye

Qin

Yang

Peng

Shiqi

2012

3 1 102 108

Abstract

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research-article

MedChemComm

2040-2503

Royal Society of Chemistry

MedChemWatch Issue 14 and Back matter

10.1039/c1md90048j

Author

Anonymous

2012

3 1 109 110

Abstract

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MedChemComm

2040-2503

Royal Society of Chemistry

Back cover

10.1039/c1md90047a

Author

Anonymous

2012

3 1 111 112

Abstract

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other