While full papers in Integrative Biology must present evidence of new biological insights, we seek to provide a venue for new methods that may not yet have revealed new insights, but that clearly have the potential to do so, and thus are of strong interest to the biomedical research community. This is in keeping with our overarching mission to provide a bridge between technology and biology. As such, we introduce a new Method section in Integrative Biology. Method articles, then, must provide a sound utility of the technology in the biological world and have clear potential to enable new insights and impact biology research.