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Lab on a Chip

Miniaturisation for chemistry, physics, biology and bioengineering



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Cover image for Issue 14, 2010, Back cover

Issue 14, 2010, Back cover

MAPS (Microfludic-system Analyzing Protein in Single-complex) is a novel system for detecting fluorescence labeled protein-complexes individually, which allows researchers to quickly uncover the ratio and dynamics of cell signal transduction.
DOI: 10.1039/C0LC90023K

Cover image for Issue 13, 2010, Back cover

Issue 13, 2010, Back cover

Embryoid bodies (EBs) are spherical aggregates of spontaneously differentiating embryonic stem cells and EB-mediated differentiation efficiency is critically dependent upon EB size. This paper presents a microfluidic device for sorting EBs into multiple size-dependent groups with high separation efficiencies.
DOI: 10.1039/C0LC90018D

Cover image for Issue 9, 2010, Back cover

Issue 9, 2010, Back cover

Rapid lysis of single cells and bacteria is demonstrated using local heating from silicon-diamond microcantilevers with integrated solid state resistive heaters.
DOI: 10.1039/C004777P


Cover image for Issue 5, 2010, Back cover

Issue 5, 2010, Back cover

This integrated microfluidic surface plasmon resonance imaging device is comprised of a serial dilution network connected to 264 individually-addressable chambers of 700 pL each. Kinetic binding analyses are conducted in parallel, and the bound analytes may be recovered from the chip for downstream analysis.
DOI: 10.1039/C002331K

Cover image for Issue 3, 2010, Back cover

Issue 3, 2010, Back cover

We present a microfluidics device that is able to focally trigger initial recruitment and subsequent aggregation of iscoid platelets by mimicking the effects of pathological changes in blood vessel geometry.
DOI: 10.1039/c000214n

Cover image for Issue 2, 2010, Back cover

Issue 2, 2010, Back cover

An artist's conception of a stream of droplets encapsulating single dye stained DNA molecules and their sequential fluorescence based interrogation to detect the presence of the encapsulated DNA molecules.
DOI: 10.1039/b925940f