Chips & Tips
Welcome to Chips & Tips - a unique and regularly updated forum for scientists in the miniaturisation field. Chips & Tips aims to provide a place where ideas and solutions can be exchanged on common practical problems encountered in the lab, which are seldom reported in the literature.
Do you
. have problems with bubble formation when injecting your sample?
. wish there was a quicker way to make prototypes?
. find connecting chips to pumps and syringes problematic?
Or
. do you have your own tricks to overcome these or similar problems?
If so, then Chips & Tips is the forum to address your requirements.
Read the tips below or see the author guidelines on how to submit your own today!
David Beebe and Glenn Walker

Chips & Tips: A simple and economical holder for casting PDMS chips
20 November 2009
Gang Li and co-workers demonstrate a simple and economical holder for casting PDMS chips

Chips & Tips: Custom made production of cheap Luer lock adapters for chip-to-syringe interfacing
20 November 2009
Claudio Nastruzzi and colleagues demonstrate "custom made" production of cheap Luer lock adapters

Chips & Tips: Plug-and-play reservoirs for microfluidics
28 October 2009
Christopher Y Wong and Georgian Ionut Ciobanu demonstrate plug-and-play reservoirs for microfluidics

Chips & Tips: A novel method for fabrication of reusable microfluidic interconnects
28 October 2009
V T Remcho and co-workers present a novel method for fabrication of reusable microfluidic interconnects

Chips & Tips: A remote syringe for cells, beads and particle injection in microfluidic channels
20 August 2009
Jean-Christophe Baret explains how to build a remote syringe for cells, beads and particle injection in microfluidic channels

Chips & Tips: How to prevent sagging during the bonding or lamination of chips with large aspect ratio chambers
24 July 2009
Jie Xu and Daniel Attinger give tips for prevent sagging when fabricating large aspect ratio chambers

Chips & Tips: Quick assessment of the stability of flow generated by a syringe pump in a microfluidic device
16 July 2009
Rachel Green and Siva Vanapalli demonstrate a rig for assessing microfluidic flow stability

Chips & Tips: A method for rapid fabrication of microfluidic devices
30 June 2009
Rajan Kumar and colleagues explain how to rapidly fabricate microfluidic devices using double-sided tape and a T-shirt transfer press

Chips & Tips: Simple and reversible bonding of glass to glass, quartz and sapphire wafers
14 May 2009
Javier Atencia and Laurie E. Locascio demonstrate a simple and reversible method for bonding of glass to glass, quartz and sapphire wafers

Chips & Tips: An inexpensive and durable epoxy mold for PDMS
22 April 2009
André Estévez-Torres and coworkers explain how to make an inexpensive and durable epoxy mold for PDMS

Chips & Tips: Interfacing of microfluidic devices
27 February 2009
Suman Chakraborty and colleagues describe a method for interfacing microfluidic devices to reservoirs and pumps

Chips & Tips: Overcoming interfacing issues by adding fumed silica
21 November 2008
Alexander Iles describes the use of fumed silica for overcoming interfacing issues

Chips & Tips: Profile measurement for microstructures made in hard material
22 October 2008
Jie Xu and Daniel Attinger explain a method for profile measurement for microstructures made in hard material

Chips & Tips: Reusable, robust NanoPort connections to PDMS chips
08 October 2008
Jesse Greener and colleagues describe how to make reusable, robust NanoPort connections to PDMS chips

Chips & Tips: Rapid prototyping of a PMMA microfluidic chip with integrated platinum electrodes
18 September 2008
Martin Arundell and co-workers report a method for rapid prototyping of PMMA microfluidic chips with integrated platinum electrodes

Chips & Tips: Bonding & Sealing of components in PDMS by deposition of micro-drops of PDMS using micropipette
09 September 2008
Arash Noori and P. Ravi Selvaganapathy describe a method for bonding and sealing of components in PDMS

Chips & Tips: Lamination of Plastic Microfluidic Devices
30 July 2008
Daniel Olivero and Z. Hugh Fan present a simple method for lamination of plastic microfluidic devices

Chips & Tips: Quick Measurement of Electroosmotic Flow Velocity
10 July 2008
Motohiko Nohmi and Juan Santiago present a simple way of estimating electroosmotic flow velocities in channel geometries with at least one intersection.

Chips & Tips: See where to punch holes easily in a PDMS microfluidic device
29 May 2008
Amy Rowat and David Weitz describe how to see where to punch holes in a PDMS microfluidic device.

Chips & Tips: Integrated Reservoirs for PDMS Microfluidic Chips
22 April 2008
T. Liu and co-workers present integrated reservoirs for PDMS microfluidic chips.

Chips & Tips: An easy temperature control system for syringe pumps
22 April 2008
Lorenzo Capretto and co-workers describe an easy temperature control system for syringe pumps.

Chips & Tips: Microfabrication Design Guidelines for Glass Micro- and Nano-fluidic Devices
18 April 2008
Dave Huber and Sumita Pennathur give some useful microfabrication design guidelines for glass micro- and nano-fluidic devices.

Chips & Tips: Bonding Upchurch® NanoPorts to PDMS
12 February 2008
Corey Koch and co-workers describe a simple method to bond Upchurch® NanoPortsT to PDMS chips.

Chips & Tips: Magnets for facile molding of via holes in PDMS
06 February 2008
Corey Koch and co-workers describe the use of magnetic molds for construction of complex PDMS devices

Chips & Tips: A foolproof method for enclosing glass-based LOC devices for electrophoresis
16 January 2008
Colin Mansfield and co-workers describe a simple method to produce a leak free and easily reusible device for electrophoresis.

Chips & Tips: Organic Solvent Compatible Reservoirs for Glass Microfluidic Chips
06 December 2007
Michael Watson and Aaron Wheeler describe an alternative to using non-solvent resistant adhesives to attach reservoirs to microfludic chips.

Chips & Tips: Preventing suspension settling during injection
21 August 2007
Ryan Cooper and Luke Lee describe how to avoid settling of suspensions during injection onto a chip.

Chips & Tips: Quick and cheap syringe-tubing interfacing
26 June 2007
Rodrigo Martinez-Duarte and Marc Madou describe a simple method to connect syringes to chips.

Chips & Tips: On-chip Electrophoresis Devices: Do's, Don'ts and Dooms
26 March 2007
Juan Santiago and co-workers provide some simple rules of thumb for success in on-chip electrophoresis

Chips & Tips: Rapid Prototyping of microfluidics
15 February 2007
Richard Holmes and Nicholas Goddard describe rapid prototyping of microfluidic systems using double sided tape.

Chips & Tips: Superior data presentation of poor quality microfluidics images
05 February 2007
Richard Holmes and Nicholas Goddard describe a simple method to manipulate video images of microfluidics for presentation in print.

Chips & Tips: In-line microfluidic bubble trap
22 November 2006
David Eddington presents a simple in-line bubble trap for microfluidic devices.

Chips & Tips: A simple interface between a PDMS microfluidic device and a syringe
13 November 2006
Jeonggi Seo and Meng H. Lean present a simple way to connect a syringe to your microfluidic device without the need for adhesive.

Chips & Tips: Vacuum filling of microfluidic devices
23 October 2006
Ivar Meyvantsson and David Beebe provide a simple method to remove bubbles when filling microfluidic chips.

Chips & Tips: Avoiding bubble injection by droplet merging
23 October 2006
Edmond Young, Aaron Wheeler and Craig Simmons present an easy way to avoid injecting bubbles along with your sample.

Chips & Tips: PDMS connectors for macro to microfluidic interfacing
23 October 2006
Swomitra Mohanty, Glennys Mensing and David Beebe report a simple fabrication of PDMS connectors to interface chips with the macro world.

