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Microfluidic and nanotechnologies for chemistry, biology, and bioengineering
Cover Gallery 2006
Lab on a Chip cover images from 2006 are available to browse here
Cover Gallery
An open-access patch-clamp chip features multiple lateral cell trapping sites raised above the bottom plane of the chip and easy fluidic access. Reproduced by permission of A. Lau.
DOI: 10.1039/b608439g
Multiple inlets along a reactive surface such as electrodes on the side wall of a microfluidic channel allows periodic replenishment of the reagent depletion boundary layer that forms on the surface, thereby increasing the overall conversion of the desired chemical process. Reproduced by permission of P. J. A. Kenis.
DOI: 10.1039/b615991p
A single heart muscle cell within a pL-scale chamber, comprising an integrated lactate microbiosensor together with field stimulation microelectrodes. Reproduced by permission of J. Cooper.
DOI: 10.1039/b608202e
The uTAS approach has evolved over the past decade into the more general lab-on-a-chip concept, literally referring to an experimentation space on a chip. Reproduced by permission of A. van den Berg.
DOI: 10.1039/b612120a
Lab-on-a-chip placed in the historic context of the earlier concepts Total Analysis Systems, the ideal sensor, and Miniaturized Analysis Systems. Reproduced by permission of A. van den Berg.
DOI: 10.1039/b613246b
Authors probe the composition of droplets circulating in microchannels by using Raman spectroscopy. Photograph supplied by H. Raguet, CNRS, and reproduced by permission of G. Cristobal.
DOI: 10.1039/B602702d
The optical cell retainer - live, non-adherent untethered cells, in a population can be individually treated and explored, pre- and post-fixation, while maintaining their identity. Reproduced by permission of M.Deutsch.
DOI: 10.1039/B603961h
A high performance monolithically integrated long-pass filter for disposable on-chip fluorescence detection. Reproduced by permission of J. deMello.
DOI: 10.1039/b609594c
Switchable surface traps for injectable bead-based chromatography in PDMS microfluidic channels. Reproduced by permission of P. Stayton.
DOI: 10.1039/B515128g
An optical tweezer driving a microfluidic pump using the spin angular momentum of light to rotate birefringent particles. Reproduced by permission of J. Cooper.
DOI: 10.1039/B601886f
Lobule-mimetic heterogeneous radical patterning of hepatic (green) and endothelial (red) cells via the MEMS chip design of enhanced field-induced dielectrophoresis snare is demonstrated. Reproduced by permission of C-H. Liu.
DOI: 10.1039/b606575a
Schematic of a microdevice with PCR chambers (red), sizing standard introduction channels (green), and electrophoresis channels (blue). Reproduced by permission of J. P. Landers.
DOI: 10.1039/B600039h
Long tubes generated on a microchip by extrusion of a lipid film through microsized apertures. Image reproduced by permission of A. Manz.
DOI: 10.1039/B517670k
Integrated microfluidic device for nucleic acid analysis. Image reproduced by permission of P. Day.
DOI: 10.1039/B603588b
Composite images of a passive microfluidic fuel cell and component metal and metal alloy thin film electrodes. Image reproduced by permission of R. Nuzzo.
DOI: 10.1039/B513829a
A cell-based micropump on-chip exploiting mechanical functions of cardiomyocytes. Image reproduced by permission of T. Kitamori.
DOI: 10.1039/B601981c
A Drosophila embryo is allowed to develop on a microfluidic platform. The authors characterise their movement through experimentation and numerical modelling. Image reproduced by permission of Rustem Ismagilov.
DOI: 10.1039/B516119c
The image shows the magnetic flux density between four magnets arranged in a square with their north poles facing the centre, simulated with FEMM-freeware. Image reproduced by permission of Nicole Pamme.
DOI: 10.1039/B513005k
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