Issue 10, 2009

Glycan determinants on the surface of a cell.

Issue 9, 2009

Integrative systems biology approach permits analysis of paracrine protein-mediated signaling in stem cells using computer models and microfluidics.

Issue 8, 2009

The image illustrates mirror image phage display as a very elegant approach to identify new D-enantiomeric peptide ligands.

Issue 7, 2009, inside

Single molecules of cytochrome c are wrapped in an ultra-thin silica shell (red) and encapsulated within surfactant micelles to produce discrete bio-inorganic nanoparticles (background TEM image).

Issue 7, 2009

An RNAi-based universal Boolean calculator that operates in mammalian cells.

Issue 6, 2009

Image illustrating the structural characterization of GABARAP-ligand interactions.

Issue 5, 2009

The image illustrates recent advances in fluorescent probe developments facilitated by diversity-oriented library approaches.

Issue 4, 2009

Image showing a lipsome containing the alpha subunit of the G protein. The binding of the drug molecule, BC5, activates the protein, modulating the release of GDP (light green) and binding of GTP (dark green). The background shows a freeze fracture EM of the liposomes.

Issue 3, 2009

The docked posure of coralyne bound to t-RNA.

Issue 2, 2009

Protein interaction network of Escherichia coli with nodes representing proteins and sizes proportional to their degree. Transcripts of proteins with high, medium and low half-lives are coloured in red, green and blue respectively.

Issue 1, 2009

The evolutionary dynamics of transposable elements show many parallels to the epidemiology of human diseases.