RSC Publishing


Publishing

 

Metallomics

A new journal covering the research fields related to biometals



Latest News

Abstract Image

Increasing in frequency from 2010

11 December 2009

2010 will see Metallomics increase in frequency to 12 issues per year


International Symposia on Advancing the Chemical Sciences

Submit abstracts and register for ISACS now

01 December 2009

Poster abstract submission and online registration now open for 2010 ISACS conferences


A methylated bismuth compound

A piece in the puzzle of bismuth toxicology

21 October 2009

Liver cells transform inorganic bismuth into potentially toxic methylated species


Registration for free online access

Fill in our simple online registration form

News archive

Previous news from Metallomics



  • Advance Articles


Contents list for Metallomics, issue 6, 2009

RSS news feed image for latest articles

Front cover
Metallomics, 2009, 1, 445
DOI: 10.1039/b921981c

front cover image for Metallomics, Issue 6, 2009

Contents and Highlights in Chemical Biology
Metallomics, 2009, 1, 447
DOI: 10.1039/b921982j

Editorial

Metallomics scope
Metallomics, 2009, 1, 457
DOI: 10.1039/b921988a

Critical Review

Recent developments in ruthenium anticancer drugs
Aviva Levina, Anannya Mitra and Peter A. Lay,  Metallomics, 2009, 1, 458
DOI: 10.1039/b904071d
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b904071d)

Generalised pathways of action of Ru(III/II) anticancer complexes (LnRu–X in the Scheme, where L are the tightly bound ligands and X is the leaving group), based on their partial hydrolysis and competitive interactions with various types of biomolecules (see Scheme), are proposed for the first time.

Papers

Beryllium uptake and related biological effects studied in THP-1 differentiated macrophages
Jian Ding, Lin Lin, Wei Hang and Xiaomei Yan,  Metallomics, 2009, 1, 471
DOI: 10.1039/b913265a
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b913265a)

Cellular beryllium content measurement indicated that the uptake of particulate BeO was much more significant than that of soluble BeSO4, suggesting the major cellular uptake pathway is phagocytosis. However, incorporated beryllium has negligible cytotoxicity to THP-1 macrophages.

Incorporation of excess gadolinium into human bone from medical contrast agents
Thomas H. Darrah, Jennifer J. Prutsman-Pfeiffer, Robert J. Poreda, M. Ellen Campbell, Peter V. Hauschka and Robyn E. Hannigan,  Metallomics, 2009, 1, 479
DOI: 10.1039/b905145g
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b905145g)

This research documents the incorporation and retention of gadolinium in bone tissue of patients exposed to chelated Gd during contrast MRI, and investigates its potential effects on health, on bone and the impacts of bone pathology on metal incorporation.

The plant metallothionein 2 from Cicer arietinum forms a single metal–thiolate cluster
Xiaoqiong Wan and Eva Freisinger,  Metallomics, 2009, 1, 489
DOI: 10.1039/b906428a
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b906428a)

The first spectroscopic characterization of metallothionein 2 from chickpea reveals its metal-binding ability for divalent metal ions and suggests the formation of a single metal–thiolate cluster.

Denaturing and non-denaturing microsolution isoelectric focussing to mine the metalloproteome
Barbara Pioselli, Caroline Munro, Andrea Raab, Christian L. Deitrich, Kriangsak Songsrirote, Jörg Feldmann and Jane Thomas-Oates,  Metallomics, 2009, 1, 501
DOI: 10.1039/b903607e
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b903607e)

Denaturing and non-denaturing conditions for solution isoelectric focussing of metalloproteins have been developed and applied to a complex metalloproteome.

Pseudo-halide derivatives of titanocene Y: synthesis and cytotoxicity studies
James Claffey, Anthony Deally, Brendan Gleeson, Megan Hogan, Luis Miguel Menéndez Méndez, Helge Müller-Bunz, Siddappa Patil, Denise Wallis and Matthias Tacke,  Metallomics, 2009, 1, 511
DOI: 10.1039/b911753a
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b911753a)

Four pseudo-halide substituted analogues of Titanocene Y were synthesised and their cytotoxicity tests on pig LLC-PK cells and a structural discussion of two derivatives are reported.

The metallomics approach: use of Fe(II) and Cu(II) footprinting to examine metal binding sites on serum albumins
Michael R. Duff, Jr.,Challa V. Kumar,  Metallomics, 2009, 1, 518
DOI: 10.1039/b910253a
RSC Prospect Icon Enhanced HTML article available

graphical abstract image (ID: b910253a)

Metal binding to serum albumins is examined by oxidative protein-cleavage chemistry, and relative affinities of multiple metal ions to particular sites on these proteins were identified using a fast and reliable chemical footprinting approach.

Back matter
Metallomics, 2009, 1, 524
DOI: 10.1039/b921998f

Back cover
Metallomics, 2009, 1, 527
DOI: 10.1039/b921983h