Advance Articles for Organic & Biomolecular Chemistry
First published on the web: 20 November 2009
The stability of imine-containing dynamic [2]rotaxanes to hydrolysis
Ken Cham-Fai Leung, Wing-Yan Wong, Fabio Aricó, Philip C. Haussmann and J. Fraser Stoddart,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915864b
First published on the web: 19 November 2009
Study on the selectivity in the electrophilic monofluorination of 2,3-allenoates with Selectfluor
: an efficient synthesis of 4-fluoro-2(5H)-furanones and 3-fluoro-4-oxo-2(E)-alkenoates
Bo Lü, Chunling Fu and Shengming Ma,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917793k
Phosphorane intermediate vs. leaving group stabilization by intramolecular hydrogen bonding in the cleavage of trinucleoside monophosphates: implications for understanding catalysis by the large ribozymes
Tuomas Lönnberg and Maarit Laine,
Org. Biomol. Chem., 2010
DOI: 10.1039/b912042d
Development of a new microwave-assisted cleavable backbone amide linker (BAL): a comparative study
Stijn Claerhout, Thibault Duchène, Dirk Tourwé and Erik V. Van der Eycken,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919365k
First published on the web: 18 November 2009
Direct fixation of [11C]-CO2 by amines: formation of [11C-carbonyl]-methylcarbamates
Alan A. Wilson, Armando Garcia, Sylvain Houle and Neil Vasdev,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916419g
First published on the web: 17 November 2009
1,1
-Binaphthyl-based imidazolium chemosensors for highly selective recognition of tryptophan in aqueous solutions
Li Yang, Song Qin, Xiaoyu Su, Fei Yang, Jingsong You, Changwei Hu, Rugang Xie and Jingbo Lan,
Org. Biomol. Chem., 2010
DOI: 10.1039/b908540h
First published on the web: 16 November 2009
Synthesis and room temperature photo-induced electron transfer in biologically active bis(terpyridine)ruthenium(II)–cytochrome c bioconjugates and the effect of solvents on the bioconjugation of cytochrome c
Joshua R. Peterson, Trevor A. Smith and Pall Thordarson,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919289a
Epimeric and amino disaccharide analogs as probes of an
-(1
6)-mannosyltransferase involved in mycobacterial lipoarabinomannan biosynthesis
Pui Hang Tam and Todd L. Lowary,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916580k
Water-solubilised BF2-chelated tetraarylazadipyrromethenes
Mariusz Tasior, Julie Murtagh, Daniel O. Frimannsson, Shane O. McDonnell and Donal F. O'Shea,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919546g
Impregnated copper on magnetite: an efficient and green catalyst for the multicomponent preparation of propargylamines under solvent free conditions
María J. Aliaga, Diego J. Ramón and Miguel Yus,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917923b
First published on the web: 13 November 2009
Total synthesis of LeA-LacNAc pentasaccharide as a ligand for Clostridium difficile toxin A
Ping Zhang, Kenneth Ng and Chang-Chun Ling,
Org. Biomol. Chem., 2010
DOI: 10.1039/b914193f
First published on the web: 12 November 2009
Identification and biosynthesis of tropone derivatives and sulfur volatiles produced by bacteria of the marine Roseobacter clade
Verena Thiel, Thorsten Brinkhoff, Jeroen S. Dickschat, Susanne Wickel, Jörg Grunenberg, Irene Wagner-Döbler, Meinhard Simon and Stefan Schulz,
Org. Biomol. Chem., 2010
DOI: 10.1039/b909133e
Stereoselective synthesis and structure–affinity relationships of bicyclic
receptor agonists
Daniel Kracht, Elisabeth Rack, Dirk Schepmann, Roland Fröhlich and Bernhard Wünsch,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915180j
Mechanism of chemical O-glycosylation: from early studies to recent discoveries
Laurel K. Mydock and Alexei V. Demchenko,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916088d
DIBAL-H mediated triple and quadruple debenzylations of perbenzylated cyclodextrins
Girish K. Rawal, Shikha Rani, Sandra Ward and Chang-Chun Ling,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915450g
First published on the web: 10 November 2009
Synthetic biology
Ali Tavassoli,
Org. Biomol. Chem., 2010
DOI: 10.1039/b913300n
A short, chemoenzymatic route to chiral
-aryl-
-amino acids using reductases from anaerobic bacteria
Anna Fryszkowska, Karl Fisher, John M. Gardiner and Gill M. Stephens,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919526b
Nickel/magnesium–lanthanum mixed oxide catalyst in the Kumada-coupling
Árpád Kiss, Zoltán Hell and Mária Bálint,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919246h
First published on the web: 09 November 2009
Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes
Stuart J. Conway, James Gardiner, Simon J. A. Grove, Melloney K. Johns, Ze-Yi Lim, Gavin F. Painter, Diane E. J. E. Robinson, Christine Schieber, Jan W. Thuring, Leon S.-M. Wong, Meng-Xin Yin, Antony W. Burgess, Bruno Catimel, Phillip T. Hawkins, Nicholas T. Ktistakis, Leonard R. Stephens and Andrew B. Holmes,
Org. Biomol. Chem., 2010
DOI: 10.1039/b913399b
An efficient and convenient Cu(OAc)2/air mediated oxidative coupling of azoles via C–H activation
Yan Li, Jun Jin, Weixing Qian and Weiliang Bao,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919396k
Cyclooctyne-based reagents for uncatalyzed click chemistry: A computational survey
Kimberly Chenoweth, David Chenoweth and William A. Goddard III,
Org. Biomol. Chem., 2009
DOI: 10.1039/b911482c
Small molecule induced control in duplex and triplex DNA-directed chemical reactions
Mikkel F. Jacobsen, Jens B. Ravnsbæk and Kurt V. Gothelf,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919387a
First published on the web: 06 November 2009
Host–guest complexations of local anaesthetics by cucurbit[7]uril in aqueous solution
Ian W. Wyman and Donal H. Macartney,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915694a
Asymmetric ruthenium-catalyzed 1,4-additions of aryl thiols to enones
Andrei B
doiu, Gerald Bernardinelli, Céline Besnard and E. Peter Kündig,
Org. Biomol. Chem., 2010
DOI: 10.1039/b918877k
First published on the web: 05 November 2009
Total synthesis of asperlicin C, circumdatin F, demethylbenzomalvin A, demethoxycircumdatin H, sclerotigenin, and other fused quinazolinones
Ming-Chung Tseng, Huei-Yun Yang and Yen-Ho Chu,
Org. Biomol. Chem., 2010
DOI: 10.1039/b910545j
Facile P,N-heterocycle synthesis via tandem aminomethylation–cyclization of H-phosphinate building blocks
Clémence Queffélec and Jean-Luc Montchamp,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917428a
A novel bimodal lipidic contrast agent for cellular labelling and tumour MRI
Nazila Kamaly, Tammy Kalber, Gavin Kenny, Jimmy Bell, Michael Jorgensen and Andrew Miller,
Org. Biomol. Chem., 2010
DOI: 10.1039/b910561a
Glycosidase inhibition: assessing mimicry of the transition state
Tracey M. Gloster and Gideon J. Davies,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915870g
First published on the web: 04 November 2009
Bis-cation salt complexation by meso-octamethylcalix[4]pyrrole: linking complexes in solution and in the solid state
Claudia Caltagirone, Nathan L. Bill, Dustin E. Gross, Mark E. Light, Jonathan L. Sessler and Philip A. Gale,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916113a
Release of nitrite from the antitubercular nitroimidazole drug PA-824 and analogues upon one-electron reduction in protic, non-aqueous solvent
Andrej Maroz, Sujata S. Shinde, Scott G. Franzblau, Zhenkun Ma, William A. Denny, Brian D. Palmer and Robert F. Anderson,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915877d
Oxidative spirocyclisation routes towards the sawaranospirolides. Synthesis of ent-sawaranospirolides C and D
Jeremy Robertson, Praful T. Chovatia, Thomas G. Fowler, Jonathan M. Withey and Daniel J. Woollaston,
Org. Biomol. Chem., 2010
DOI: 10.1039/b918091e
First published on the web: 02 November 2009
Synthesis and conformational analysis of D-2
-deoxy-2
,2
-difluoro-4
-dihydro-4
-thionucleosides
Feng Zheng, Lin Fu, Renxiao Wang and Feng-Ling Qing,
Org. Biomol. Chem., 2010
DOI: 10.1039/b914679b
Matrix mechanics and receptor–ligand interactions in cell adhesion
Dewi Harjanto and Muhammad H. Zaman,
Org. Biomol. Chem., 2010
DOI: 10.1039/b913064k
First published on the web: 30 October 2009
Mirabilins revisited: polyketide alkaloids from a southern Australian marine sponge, Clathria sp.
Mohamed El-Naggar, Melissa Conte and Robert J. Capon,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915624k
Neutral push-pull chromophores for nonlinear optical imaging of cell membranes
Cyril Barsu, Rouba Cheaib, Stéphane Chambert, Yves Queneau, Olivier Maury, Davy Cottet, Hartmut Wege, Julien Douady, Yann Bretonnière and Chantal Andraud,
Org. Biomol. Chem., 2010
DOI: 10.1039/b915654b
First published on the web: 29 October 2009
Effect of the allylic substituents on ring closing metathesis: the total synthesis of stagonolide B and 4-epi-stagonolide B
Awadut G. Giri, Mohabul A. Mondal, Vedavati G. Puranik and Chepuri V. Ramana,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916198h
Asymmetric Michael addition reaction of 3-substituted-N-Boc oxindoles to activated terminal alkenes catalyzed by a bifunctional tertiary-amine thiourea catalyst
Xin Li, Zhi-Guo Xi, Sanzhong Luo and Jin-Pei Cheng,
Org. Biomol. Chem., 2010
DOI: 10.1039/b918644a
The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase
Wei Ge, Ian J. Clifton, Jeanette E. Stok, Robert M. Adlington, Jack E. Baldwin and Peter J. Rutledge,
Org. Biomol. Chem., 2010
DOI: 10.1039/b910170e
First published on the web: 28 October 2009
Synthesis of dihydrodehydrodiconiferyl alcohol: the revised structure of lawsonicin
Junxiu Meng, Tao Jiang, Huma Aslam Bhatti, Bina S. Siddiqui, Sally Dixon and Jeremy D. Kilburn,
Org. Biomol. Chem., 2010
DOI: 10.1039/b918179b
Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide–alkyne 1,3-dipolar cycloaddition
Virginie Algay, Ishwar Singh and Frances Heaney,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917450h
Rapid two-step synthesis of drug-like polycyclic substances by sequential multi-catalysis cascade reactions
Dhevalapally B. Ramachary, Rumpa Mondal and Chintalapudi Venkaiah,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920152a
First published on the web: 27 October 2009
Topically resolved intramolecular CH-
interactions in phenylalanine derivatives
W. Brian Jennings, Noel J. P. McCarthy, Padraig Kelly and John F. Malone,
Org. Biomol. Chem., 2009
DOI: 10.1039/b916021n
Dendron-anchored organocatalysts: the asymmetric reduction of imines with trichlorosilane, catalysed by an amino acid-derived formamide appended to a dendron
Marek Figlus, Stuart T. Caldwell, Dawid Walas, Gulen Yesilbag, Graeme Cooke, Pavel Ko
ovský, Andrei V. Malkov and Amitav Sanyal,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916601g
First published on the web: 26 October 2009
Clickable fluorescent dyes for multimodal bioorthogonal imaging
Lun K. Tsou, Mingzi M. Zhang and Howard C. Hang,
Org. Biomol. Chem., 2009
DOI: 10.1039/b917119n
Hypervalent iodine(III)-mediated oxidation of aldoximes to N-acetoxy or N-hydroxy amides
Harisadhan Ghosh and Bhisma K. Patel,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917096k
Assessing the cluster glycoside effect during the binding of concanavalin A to mannosylated artificial lipid rafts
Gavin T. Noble, Sabine L. Flitsch, Kwan Ping Liem and Simon J. Webb,
Org. Biomol. Chem., 2009
DOI: 10.1039/b910976e
Highly efficient synthesis of medium-sized lactones via oxidative lactonization: concise total synthesis of isolaurepan
Makoto Ebine, Yuto Suga, Haruhiko Fuwa and Makoto Sasaki,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919673k
Sialidase substrate specificity studies using chemoenzymatically synthesized sialosides containing C5-modified sialic acids
Hongzhi Cao, Yanhong Li, Kam Lau, Saddam Muthana, Hai Yu, Jiansong Cheng, Harshal A. Chokhawala, Go Sugiarto, Lei Zhang and Xi Chen,
Org. Biomol. Chem., 2009
DOI: 10.1039/b916305k
Total synthesis of (5R,6R,8R,9S)-(-)-5,9Z-indolizidine 221T using sulfinimine-derived N-sulfinyl
-amino ketones
Franklin A. Davis, Minsoo Song, Hui Qiu and Jing Chai,
Org. Biomol. Chem., 2009
DOI: 10.1039/b915796d
Diastereoselective synthesis of (±)-1
,4
-dimethyluridine
Guillaume Sautrey, Damien Bourgeois and Christian Périgaud,
Org. Biomol. Chem., 2010
DOI: 10.1039/b912411j
First published on the web: 23 October 2009
Diagnostic fragmentations of adducts formed between carbanions and carbon disulfide in the gas phase. A joint experimental and theoretical study
Micheal J. Maclean, Scott Walker, Tianfang Wang, Peter C. H. Eichinger, Patrick J. Sherman and John H. Bowie,
Org. Biomol. Chem., 2010
DOI: 10.1039/b916477d
Microwave-assisted three-component coupling-addition-SNAr (CASNAR) sequences to annelated 4H-thiopyran-4-ones
Benjamin Willy, Walter Frank and Thomas J. J. Müller,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917627f
An efficient copper-catalyzed synthesis of hexahydro-1H- phenothiazines
D. J. C. Prasad and Govindasamy Sekar,
Org. Biomol. Chem., 2009
DOI: 10.1039/b916664e
First published on the web: 22 October 2009
Mechanism of glycoside hydrolysis: A comparative QM/MM molecular dynamics analysis for wild type and Y69F mutant retaining xylanases
Mahmoud E. S. Soliman, J. Javier Ruiz Pernía, Ian R. Greig and Ian H. Williams,
Org. Biomol. Chem., 2009
DOI: 10.1039/b911644c
Carbamate complexation by urea-based receptors: studies in solution and the solid state
Peter. R. Edwards, Jennifer. R. Hiscock, Philip. A. Gale and Mark. E. Light,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917140a
First published on the web: 21 October 2009
Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binder BRACO-19
Julien Debray, Walid Zeghida, Muriel Jourdan, David Monchaud, Marie-Louise Dheu-Andries, Pascal Dumy, Marie-Paule Teulade-Fichou and Martine Demeunynck,
Org. Biomol. Chem., 2009
DOI: 10.1039/b912716j
An enantiospecific route towards taiwaniaquinoids. First synthesis of (-)-taiwaniaquinone H and (-)-dichroanone
Enrique Alvarez-Manzaneda, Rachid Chahboun, Eduardo Cabrera, Esteban Alvarez, Ali Haidour, Jose Miguel Ramos, Ramón Alvarez-Manzaneda, Yahia Charrah and Hakima Es-Samti,
Org. Biomol. Chem., 2009
DOI: 10.1039/b916209g
Reactions of 2-(pyrrol-1-yl)benzyl radicals and related species under flash vacuum pyrolysis conditions
J. I. G. Cadogan, Bernard A. J. Clark, Daniel Ford, Ranald J. MacDonald, Andrew D. MacPherson, Hamish McNab, Iain S. Nicolson, David Reed and Craig C. Sommerville,
Org. Biomol. Chem., 2009
DOI: 10.1039/b914965a
First published on the web: 20 October 2009
Syntheses of difluorinated carbasugar phosphates from trifluoroethanol
Timo Anderl, Christophe Audouard, Afjal Miah, Jonathan M. Percy, Giuseppe Rinaudo and Kuldip Singh,
Org. Biomol. Chem., 2009
DOI: 10.1039/b914068a
Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis
Tae-gyu Nam, Susheel J. Nara, Irène Zagol-Ikapitte, Thomas Cooper, Luca Valgimigli, John A. Oates, Ned A. Porter, Olivier Boutaud and Derek A. Pratt,
Org. Biomol. Chem., 2009
DOI: 10.1039/b912528k



