Centenary Prize 2010 Winner
Massachusetts Institute of Technology
For his pioneering studies of biological interactions involving metal ions, with a particular focus on the reactions, physical and structural properties of metal complexes.
About the Winner
Stephen J. Lippard is the Arthur Amos Noyes Professor of Chemistry at the Massachusetts Institute of Technology where he was Head of the Chemistry Department from 1995-2005.
He was born in Pittsburgh, Pennsylvania and educated at Haverford College (B. A. in Chemistry) and the Massachusetts Institute of Technology (Ph. D. in Inorganic Chemistry). After a postdoctoral year at MIT during 1965-66, he joined the faculty of Columbia University where he served until moving to MIT in 1983.
Lippard's research activities span the fields of inorganic chemistry, biological chemistry, and neurochemistry. Included are studies to understand and improve platinum anticancer drugs, the synthesis of dimetallic complexes as models for non-heme iron metalloenzymes, structural and mechanistic investigations of methane monooxygenase and related bacterial non-heme diiron multicomponent monooxygenases, and inorganic neurotransmitters, especially nitric oxide and zinc.
He published 750 papers on these and other topics and co-authored a popular textbook with Jeremy Berg entitled "Principles of Bioinorganic Chemistry." He has supervised the Ph. D. thesis research of over 100 graduate students and more than that number of postdoctoral associates. His honors include election to the National Academy of Sciences, the National Institute of Medicine, and the American Academy of Arts and Sciences.
He holds several honorary D. Sc. degrees, has been elected to honorary memberships in the Italian Chemical Society, the Royal Irish Academy, and the German National Academy of Sciences Leopoldina, and has won numerous awards and medals from the American Chemical Society. He was awarded the 2004 National Medal of Science by President George W. Bush.